Neill Liptrott

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Reader in Pharmacology and Immunocompatibility

University of Liverpool

United Kingdom

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About

Neill Liptrott is a Reader in Pharmacology and Immunocompatibility at the University of Liverpool, UK. His research focuses on the interaction of nanoparticles with immune cells, gene expression modulation, and the immunological outcomes of nanomaterials. Recent publications include studies on mast cell gene expression, macrophage phenotype, and the inflammatory effects of stem cell-derived treatments.

Recent Grants

Grant: Close

Building a UK IntraCellular Drug Delivery Centre (ICDDC)

Open Date: 2023-01-01

Close Date:

Grant: Open

SINPAIN: A game changer for the treatment of osteoarthritis: a cost effective combined advanced therapy to treat knee osteoarthritis (SINPAIN)

Open Date: 2022-04-30

Close Date: 2026-10-31

Grant: Close

Multi-modal high resolution preclinical PET+SPECT+CT scanner

Open Date: 2018-07-01

Close Date: 2023-07-01

Grant: Close

Bioengineered substrates for human pluripotent stem cell culture

Open Date: 2016-11-01

Close Date: 2018-10-31

Articles (18)

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2025

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (14)

Christian M. Hedrich

UNITED KINGDOM

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Paul McNamara

Professor in Child Health

University of Liverpool

UNITED KINGDOM

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Arthur Taylor

University of Liverpool

UNITED KINGDOM

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Rebecca Jensen

Lecturer

University of Liverpool

UNITED KINGDOM

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Patricia Murray

Professor of stem cell biology and regenerative medicine

University of Liverpool

UNITED KINGDOM

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Andrew Owen

University of Liverpool

UNITED KINGDOM

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James Hobson

University of Liverpool

UNITED KINGDOM

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Bettina Wilm

Senior Lecturer

University of Liverpool

UNITED KINGDOM

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Amy Chadwick

Lecturer

University of Liverpool

UNITED KINGDOM

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Tamiris Borges da Silva

University of Oxford

UNITED KINGDOM

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Tom McDonald

Reader in Sustainable Materials

The University of Manchester

UNITED KINGDOM

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Larisa Poluektova

Professor

University of Nebraska Medical Center

UNITED STATES

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Alexander Plant-Hately

University of Liverpool

UNITED KINGDOM

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Giancarlo Biagini

Deputy Head of Department (Professor)

Liverpool School of Tropical Medicine

UNITED KINGDOM

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Neill Liptrott

Research Interests

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About

Recent Grants

Articles (18)

Nanoparticles may influence mast cells gene expression profiles without affecting their degranulation function.

Redefining LNP composition: phospholipid and sterol-driven modulation of mRNA expression and immune outcomes

Interlaboratory comparison of endotoxin contamination assessment of nanomaterials

Nano(bio)Materials Do Not Affect Macrophage Phenotype—A Study Conducted by the REFINE Project

Interlaboratory comparison of endotoxin contamination assessment of nanomaterials.

Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations

Age-differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - Effects of vitamin D

Fate of intravenously administered umbilical cord mesenchymal stromal cells and interactions with the host's immune system

Intravenous Administration of Human Umbilical Cord Mesenchymal Stromal Cells Leads to an Inflammatory Response in the Lung

Application of KU812 cells for assessing complement activation related effects by nano(bio)materials

Umbilical cord mesenchymal stromal cell-derived extracellular vesicles lack the potency to immunomodulate human monocyte-derived macrophages in vitro

Linear and branched polymer prodrugs of the water-soluble nucleoside reverse-transcriptase inhibitor emtricitabine as structural materials for long-acting implants

Firefly luciferase offers superior performance to AkaLuc for tracking the fate of administered cell therapies

Exposure of human immune cells, to the antiretrovirals efavirenz and lopinavir, leads to lower glucose uptake and altered bioenergetic cell profiles through interactions with SLC2A1

Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics

An inter-laboratory comparison of an NLRP3 inflammasome activation assay and dendritic cell maturation assay using a nanostructured lipid carrier and a polymeric nanomedicine, as exemplars.

Physiologically based pharmacokinetic modeling of intravenously administered nanoformulated substances.

Assessment of changes in autophagic vesicles in human immune cell lines exposed to nano particles

Collaborators (14)

Christian M. Hedrich

Paul McNamara

Arthur Taylor

Rebecca Jensen

Patricia Murray

Andrew Owen

James Hobson

Bettina Wilm

Amy Chadwick

Tamiris Borges da Silva

Tom McDonald

Larisa Poluektova

Alexander Plant-Hately

Giancarlo Biagini

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