Giancarlo Biagini

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Deputy Head of Department (Professor)

Liverpool School of Tropical Medicine

United Kingdom

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About

Giancarlo Biagini is a Deputy Head of Department and Professor at the Liverpool School of Tropical Medicine in the UK. His research focuses on innovative approaches to malaria control, the assessment of antiviral treatments for COVID-19, and the study of infectious diseases through controlled human infection models. Recent articles highlight his work on the mosquitocidal properties of Nitisinone, the impact of co-infections on disease severity, and the implications of vitamin D on SARS-CoV-2 infection.

Recent Grants

Grant: Close

Epistatis and antimicrobial drug resistance in tuberculosis

Open Date: 2021-10-03

Close Date: 2025-09-29

Grant: Close

MICA: Defining the two-step relay mechanism of action of the 8-aminoquinolines: A precondition for optimal combination therapies for relapse malaria

Open Date: 2021-09-05

Close Date: 2024-09-04

Grant: Close

Development of sustainable academic-industry partnerships: Untapping breakthrough innovation for the treatment and management of infectious diseases

Open Date: 2021-06-30

Close Date: 2024-06-29

Grant: Close

UKRI COVID19 Doctoral Funding Liverpool School of Tropical Medicine

Open Date: 2021-03-31

Close Date: 2022-03-30

Grant: Close

Tropical Infectious Disease Consortium (TIDC) – Confidence in Concept 2019

Open Date: 2020-03-30

Close Date: 2022-03-29

Articles (17)

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2025

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2023

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2022

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (21)

Álvaro Acosta Serrano

Professor of Vector Biology

University of Notre Dame

UNITED STATES

Giancarlo Biagini

Research Interests

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About

Recent Grants

Articles (17)

Nitisinone’s mosquitocidal properties hold promise for malaria control

A feasibility study of controlled human infection with intradermal Bacillus Calmette–Guérin (BCG) injection: Pilot BCG controlled human infection model

Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19

Assessment of Favipiravir and Remdesivir in Combination for SARS-CoV-2 Infection in Syrian Golden Hamsters

Practical considerations for a TB controlled human infection model (TB-CHIM); the case for TB-CHIM in Africa, a systematic review of the literature and report of 2 workshop discussions in UK and Malawi

Age-differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - Effects of vitamin D

A Quantitative Method for the Study of HIV-1 and Mycobacterium tuberculosis Coinfection

Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis

Attaching protein-adsorbing silica particles to the surface of cotton substrates for bioaerosol capture including SARS-CoV-2.

Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.

Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials

Remdesivir–ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2

SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells

Enantioselective Synthesis and Profiling of Potent, Nonlinear Analogues of Antimalarial Tetraoxanes E209 and N205

Therapeutic Potential of Nitazoxanide: An Appropriate Choice for Repurposing versus SARS-CoV-2?

Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.

The cytochrome bc<sub>1</sub> complex as an antipathogenic target.

Collaborators (21)

Álvaro Acosta Serrano

Christian M. Hedrich

Paul McNamara

Martine Smit

Steve Ward

Mike Barrett

Lee Haines

Jelle van den Bor

David Matthews

Neill Liptrott

Kondwani Jambo

Andrew Owen

Lee Tatham

Aitor Casas-Sanchez

Anja Kipar

Stephen Gordon

Brigitte Meunier

Lance Turtle

Daniela M Ferreira

Neil Berry

Edward Patterson

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