Nelly Joseph-Mathurin

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Assistant Professor

Washington University in St. Louis

United States

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About

Nelly Joseph-Mathurin is an Assistant Professor at Washington University in St. Louis, USA. Her research focuses on Alzheimer's disease, particularly investigating the impact of genetic mutations on cognitive decline, brain atrophy, and amyloid pathology. She has contributed to a variety of studies utilizing advanced imaging techniques to understand the progression and underlying mechanisms of dementia in genetically predisposed populations.

Recent Grants

Grant: Open

Evaluation of the neurovascular unit in the setting of pathogenesis and treatment of autosomal dominant Alzheimer disease

Open Date: 2023-03-01

Close Date: 2028-02-29

Grant: Close

Genotype in dominantly inherited AD for clinical trial design

Open Date: 2020-01-01

Close Date:

Articles (13)

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2025

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2025

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2024

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (16)

William Klunk

Distinguished Professor

University of Pittsburgh

UNITED STATES

Nelly Joseph-Mathurin

Research Interests

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Recent Grants

Articles (13)

Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia.

Baseline and longitudinal changes in cortical thickness and hippocampal volume predict cognitive decline

Presenilin‐1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage

Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)

APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression

Amyloid‐Related Imaging Abnormalities in the DIAN‐TU‐001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease

Progressive White Matter Injury in Preclinical Dutch Cerebral Amyloid Angiopathy

Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease

Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease.

Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease

Modeling autosomal dominant Alzheimer's disease with machine learning.

Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease

Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease.

Collaborators (16)

William Klunk

Alisha Daniels

Suzanne Schindler

Gerald Reischl

Kazushi Suzuki

James Noble

John Morris

Nick Fox

Todd Kuffner

Charlene Supnet

Johannes Levin

Brian Gordon

Cyril Pottier

Qing Wang

Clifford Jack

Jason Hassenstab

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