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Nicholas Harmer

University of Exeter

United Kingdom

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Research Interests

Microbiology

50%

Biochemistry

40%

Antimicrobial Research

30%

Inflammatory Biology

20%

Laboratory Medicine

20%

Chemical Biology

20%

Macrophage Biology

20%

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Articles16

Small but mighty: the power of microcrystals in structural biology

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Year:

2025

Structure and catalytic mechanism of methylisocitrate lyase, a potential drug target against Coxiella burnetii

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Year:

2025

Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors

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Year:

2025

Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like β-lactamases

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Year:

2025

Inhibition of macrophage infectivity potentiator in Burkholderia pseudomallei suppresses pro-inflammatory responses in murine macrophages.

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Year:

2024

The High-Efficiency Degradation of Multiple Mycotoxins by Lac-W Laccase in the Presence of Mediators

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Year:

2024

Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR

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Year:

2023

Fluorescent probe for the identification of potent inhibitors of the macrophage infectivity potentiator (Mip) protein of Burkholderia pseudomallei

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Year:

2023

The ROK kinase N-acetylglucosamine kinase uses a sequential random enzyme mechanism with successive conformational changes upon each substrate binding

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Year:

2023

The natriuretic peptide receptor agonist osteocrin disperses <i>Pseudomonas aeruginosa</i> biofilm.

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Year:

2023

A Murder Mystery Gamification Session to Consolidate Analytical Biochemical Techniques Learning

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Year:

2023

Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus

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Year:

2023

Pseudomonas aeruginosa Biofilm Dispersion by the Human Atrial Natriuretic Peptide

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Year:

2022

Unique Data Sets and Bespoke Laboratory Videos: Teaching and Assessing of Experimental Methods and Data Analysis in a Pandemic

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Year:

2021

Drug screening to identify compounds to act as co-therapies for the treatment of Burkholderia species

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Year:

2021

Using enzyme cascades in biocatalysis: Highlight on transaminases and carboxylic acid reductases

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Year:

2020

Collaborators15

Jonathan West

University of Southampton

UNITED KINGDOM

sylvie CHEVALIER

Professor in Molecular Microbiology, Director

University of Rouen

FRANCE

Sophie Rodrigues

Maitre de conférences / Associate professor

Université de Bretagne Occidentale

FRANCE

Alison Hill

Senior Lecturer

University of Exeter

UNITED KINGDOM

Maria Emilia Dueñas

Newcastle University

UNITED KINGDOM

Eric Kipnis

Université de Lille

FRANCE

Benesh Joseph

Professor

Freie Universität Berlin

GERMANY

David Gray

Head of Biology

University of Dundee

UNITED KINGDOM

Lukas Kirchner

Head of laboratory

GERMANY

Albert Guskov

Scientific Staff, Associate Professor, Universitair hoofddocent

University of Groningen

NETHERLANDS

Angela Tramonti

ITALY

Bettina Siebers

Professor

Universität Duisburg-Essen

GERMANY

Jua Iwasaki

Telethon Kids Institute

AUSTRALIA

Florie Desriac

Lecturer

Université de Caen Normandie

FRANCE

Nicole Bzdyl

University of Western Australia

AUSTRALIA

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