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Nicholas Tonks

Caryl Boies Professor of Cancer Research

Cold Spring Harbor Laboratory

United States

Research Interests

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Articles (11)

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2026

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2026

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2026

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2026

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2026

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2025

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2024

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2024

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2023

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2023

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2023

Collaborators (4)

Leemor Joshua-Tor

Professor and HHMI Investigator

UNITED STATES

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Linda Van Aelst

Professor

Cold Spring Harbor Laboratory

UNITED STATES

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Erika Tse-Luen Wee

Research Assistant Professor

Cold Spring Harbor Laboratory

UNITED STATES

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Darryl Pappin

Associate Professor

Cold Spring Harbor Laboratory

UNITED STATES

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Nicholas Tonks

Research Interests

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Articles (11)

Identification and Validation of an Inhibitor of the Protein Kinases PIM and DYRK

Small-molecule inhibitors of the protein kinase DYRK as potential therapeutic candidates in cancer

PTP1B inhibition promotes microglial phagocytosis in Alzheimer’s disease models by enhancing SYK signaling

Ganaxolone, an approved therapy for CDKL5-deficiency disorder, is an inhibitor of PTP1B

The dual-specificity phosphatase JSP1 regulates neutrophil adhesion via integrin-SRC signaling in vascular inflammation

Mechanisms, functions and therapeutic targeting of protein tyrosine phosphatases

PTPN23-dependent ESCRT machinery functions as a cell death checkpoint

Famotidine increases cellular phospho-tyrosine levels

Manipulating PTPRD function with ectodomain antibodies

Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks

Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow

Collaborators (4)

Leemor Joshua-Tor

Linda Van Aelst

Erika Tse-Luen Wee

Darryl Pappin

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