Nigel Temperton

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Professor of Molecular Virology

University of Kent

United Kingdom

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Recent Grants

Grant: Close

nCoV: Developing CoV-bnMABs for therapy of highly pathogenic coronaviruses including SARS-CoV-2

Open Date: 2020-03-01

Close Date: 2021-03-01

Grant: Close

Digital Immune Optimized and Selected Pan-Influenza Vaccine Antigens (DIOS-PIVa)

Open Date: 2019-03-31

Close Date: 2021-03-30

Grant: Close

Collaboration on Diagnosis of Emerging Viruses (CoDEV)

Open Date: 2014-06-01

Close Date: 2018-06-01

Grant: Close

An alternative neutralization assay for H5N1 influenza A virus using retroviral pseudotypes

Open Date: 2006-09-30

Close Date: 2008-09-29

Grant: Close

Digital Immune Optimized and Selected Universal Influenza Vaccine Antigens (DIOS-UIVA)

Open Date:

Close Date: 2021-08-01

Articles (20)

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Collaborators (8)

Benedikt Asbach

University of Regensburg

GERMANY

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Jonathan Heeney

Professor of Comparative Pathology

University of Cambridge

UNITED KINGDOM

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Alan Parker

Professor of Translational Virotherpies

Cardiff University

UNITED KINGDOM

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Uday Kishore

UNITED ARAB EMIRATES

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Alexander Mentzer

Academic Cllinical Lecturer

University of Oxford

UNITED KINGDOM

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Chang Liu

University of Oxford

UNITED KINGDOM

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Kelly Andreia Sullivan da Costa

University College London

UNITED KINGDOM

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Simon Scott

Lecturer in Molecular Biology

University of Kent

UNITED KINGDOM

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Nigel Temperton

Research Interests

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Recent Grants

Articles (20)

Conference Report: LPMHealthcare Emerging Viruses 2023 (EVOX23): Pandemics—Learning from the Past and Present to Prepare for the Future

Antigenic sin and multiple breakthrough infections drive converging evolution of COVID-19 neutralizing responses.

Immune signature in vaccinated versus non-vaccinated aged people with COVID-19 pneumonia.

Centenarians, semi and supercentenarians, COVID-19 and Spanish flu: a serological assessment to gain insight into the resilience of older centenarians to COVID-19.

Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection

The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86

A pan-influenza monoclonal antibody neutralizes H5 strains and prophylactically protects through intranasal administration

Immunological insights into COVID-19 in Southern Nigeria

Application and comparison of lyophilisation protocols to enhance stable long-term storage of filovirus pseudotypes for use in antibody neutralisation tests

Differential T-cell and antibody responses induced by mRNA versus adenoviral vectored COVID-19 vaccines in patients with immunodeficiencies.

Capture and inactivation of viral particles from bioaerosols by electrostatic precipitation

Novel intranasal vaccine targeting SARS-CoV-2 receptor binding domain to mucosal microfold cells and adjuvanted with TLR3 agonist Riboxxim™ elicits strong antibody and T-cell responses in mice.

Pseudotyped Viruses for Influenza.

Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein

Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein

Studying longitudinal neutralising antibody levels against Equid herpesvirus 1 in experimentally infected horses using a novel pseudotype based assay.

A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses

Influenza A (N1-N9) and Influenza B (B/Victoria and B/Yamagata) Neuraminidase Pseudotypes as Tools for Pandemic Preparedness and Improved Influenza Vaccine Design

Vaccination and protective immunity to SARS-CoV-2 omicron variants in people with immunodeficiencies.

Analysis of Antibody Neutralisation Activity against SARS-CoV-2 Variants and Seasonal Human Coronaviruses NL63, HKU1, and 229E Induced by Three Different COVID-19 Vaccine Platforms

Collaborators (8)

Benedikt Asbach

Jonathan Heeney

Alan Parker

Uday Kishore

Alexander Mentzer

Chang Liu

Kelly Andreia Sullivan da Costa

Simon Scott

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