Ning Ma

Research Assistant Professor

Beckman Research Institute, City of Hope

United States

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Ning Ma is a Research Assistant Professor at the City of Hope Beckman Research Institute in the United States. His research areas focus on protein-protein interactions, the activity of small GTPases, molecular dynamics modeling, and G protein-coupled receptor (GPCR) signaling. Recent publications include investigations into the cooperativity of PROTAC complexes and the structural dynamics of GPCRs and their interactions with cellular lipids.

Articles (18)

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2025

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2020

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2020

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2020

Collaborators (13)

Wijnand Jacobus Cornelis van der Velden

Københavns Universitet

DENMARK

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Nigel W. Bunnett

Professor and Interim Chair

New York University

UNITED STATES

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Mingli Li

Assistant Professor

California State University Chico

UNITED STATES

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Ichie Ojiro

NYU Langone Health

UNITED STATES

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Arun Wiita

Associate Professor

University of California, San Francisco

UNITED STATES

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Stéphane A. Laporte

McGill University

CANADA

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Claire A. de March

Assistant professor (Chargée de recherche) CNRS

Université Paris-Saclay

FRANCE

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Teresa Sadras

Laboratory Head

Olivia Newton-John Cancer Research Institute

AUSTRALIA

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David Gloriam

Københavns Universitet

DENMARK

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Christian Billesbølle

University of California, San Francisco

UNITED STATES

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Ajit Prakash

University of North Carolina

UNITED STATES

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Dmitry Veprintsev

Professor of Molecular and Cellular Pharmacology

University of Nottingham

UNITED KINGDOM

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Sivaraj Sivaramakrishnan

UNITED STATES

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Ning Ma

Research Interests

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Articles (18)

Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexes

Disordered C-Terminus Plays a Critical Role in the Activity of the Small GTPase Ran

BaNDyT: Bayesian Network Modeling of Molecular Dynamics Trajectories

Myosin VI drives arrestin-independent internalization and signaling of GPCRs

Engineered odorant receptors illuminate the basis of odour discrimination

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f

A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state

Bayesian network models identify cooperative GPCR:G protein interactions that contribute to G protein coupling

Cellular lipids regulate the conformational ensembles of the disordered intracellular loop 3 in β2-adrenergic receptor

A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens

Structural basis of odorant recognition by a human odorant receptor

Autoregulation of GPCR signalling through the third intracellular loop

Catalytic site mutations confer multiple states of G protein activation

Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity

Activation mechanism of the class D fungal GPCR dimer Ste2

IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells.

Structure of the class D GPCR Ste2 dimer coupled to two G proteins

Activation Microswitches in Adenosine Receptor A2A Function as Rheostats in the Cell Membrane

Collaborators (13)

Wijnand Jacobus Cornelis van der Velden

Nigel W. Bunnett

Mingli Li

Ichie Ojiro

Arun Wiita

Stéphane A. Laporte

Claire A. de March

Teresa Sadras

David Gloriam

Christian Billesbølle

Ajit Prakash

Dmitry Veprintsev

Sivaraj Sivaramakrishnan

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