Nobuyuki Matoba

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Professor

University of Louisville School of Medicine

United States

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Recent Grants

Grant: Close

Preclinical validation of oral therapeutic lead proteins targeting epithelial GM1 ganglioside for ulcerative colitis therapy

Open Date: 2020-06-20

Close Date: 2024-03-31

Grant: Close

Investigation of a lectibody targeting tumor-associated oligomannose glycans

Open Date: 2018-02-08

Close Date: 2020-01-31

Grant: Close

Griffithsin-based Rectal Microbicides for PREvention of Viral ENTry (PREVENT)

Open Date: 2014-07-01

Close Date: 2019-06-30

Grant: Close

Plant-produced Actinohivin as a Candidate HIV Microbicide

Open Date: 2010-06-10

Close Date: 2012-07-14

Grant: Close

Plant-produced Actinohivin as a Candidate HIV Microbicide

Open Date: 2010-06-10

Close Date: 2016-09-30

Articles (10)

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2024

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2023

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2022

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2022

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2022

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2021

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2020

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2020

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2020

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2020

Collaborators (2)

Hadrien Peyret

Assistant Professor

University of Nottingham

UNITED KINGDOM

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Kyung Hong

Associate Professor

Western New England University

UNITED STATES

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Nobuyuki Matoba

Research Interests

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Recent Grants

Articles (10)

Lectibodies as antivirals

The Unfolded Protein Response and Its Implications for Novel Therapeutic Strategies in Inflammatory Bowel Disease.

Impact of glycoengineering and antidrug antibodies on the anticancer activity of a plant‐made lectin‐Fc fusion protein

Pharmacokinetics and Safety Studies in Rodent Models Support Development of EPICERTIN as a Novel Topical Wound-Healing Biologic for Ulcerative Colitis.

Antitumor activity of a lectibody targeting cancer-associated high-mannose glycans

Spray-Dried Formulation of Epicertin, a Recombinant Cholera Toxin B Subunit Variant That Induces Mucosal Healing

Isolation and detection of a KDEL-tagged recombinant cholera toxin B subunit from <i>Nicotiana benthamiana</i>.

Safety and Efficacy of Avaren-Fc Lectibody Targeting HCV High-Mannose Glycans in a Human Liver Chimeric Mouse Model.

Metastasis of cholangiocarcinoma is promoted by extended high-mannose glycans.

Co-expression of human calreticulin significantly improves the production of HIV gp140 and other viral glycoproteins in plants.

Collaborators (2)

Hadrien Peyret

Kyung Hong

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