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Orla Hardiman

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Professor of Neurology

Trinity College Dublin

Ireland

Research Interests

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Recent Grants

Grant: Open

Mobility mapping: Working with people with multiple sclerosis to map real-world walking experiences to digital mobility outcome measures, to improve clinical assessment.

Open Date: 2024-12-01

Close Date: 2028-03-31

Grant: Open

FutureNeuro

Open Date: 2024-06-01

Close Date: 2027-05-01

Grant: Close

PRECISION ALS

Open Date: 2020-12-01

Close Date: 2025-11-01

Grant: Close

USING TELEHEALTH TO ENHANCE MANAGEMENT OF VULNERABLE GROUPS DURING THE COVID-19 PANDEMIC

Open Date: 2020-01-01

Close Date:

Grant: Close

Biological Resource Analysis to Identify New Mechanisms and phenotypes in Neurodegenerative Diseases “BRAINMEND”

Open Date: 2018-02-01

Close Date: 2022-01-31

Articles (20)

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Collaborators (27)

Dara Meldrum

Associate Professor

Trinity College Dublin

IRELAND

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Muthuraman Muthuraman

University Hospital Würzburg

GERMANY

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Edmund Gilbert

Lecturer

Royal College of Surgeons in Ireland

IRELAND

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Philippe Couratier

Professeur Neurologie

Université de Limoges

FRANCE

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Zachary Simmons

Pennsylvania State University

UNITED STATES

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Ahmad Al Khleifat

King’s College London

UNITED KINGDOM

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David Schultz

Head of Neurology and Stroke

AUSTRALIA

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Lara McManus

Research Assistant Professor

Trinity College Dublin

IRELAND

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Peter Munch Andersen

Professor of Neurology (67% of time)

Umea University

SWEDEN

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Gianpiero Cavalleri

Professor of Human Genetics

IRELAND

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Russell McLaughlin

Ussher Assistant Professor in Genome Analysis

Trinity College Dublin

IRELAND

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Roisin Mc Mackin

Assistant Professor

Trinity College Dublin

IRELAND

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philippe corcia

Professeur

Université François-Rabelais

FRANCE

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Caroline Ingre

Karolinska Institutet

SWEDEN

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Johnathan Cooper‐Knock

Consultant Neurologist and Senior Lecturer in Neurogenetics

University of Sheffield

UNITED KINGDOM

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Umberto Manera

University of Turin

ITALY

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Ammar Al-Chalabi

Professor of Neurology and Complex Disease Genetics

King’s College London

UNITED KINGDOM

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Peter Bede

Professor in Neurology

Trinity College Dublin

IRELAND

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Julian Großkreutz

Chair of Precision Neurology

University of Lübeck

GERMANY

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Jinsy Andrews

Director of the ALS Center & Director of Clinical Trials, Professor of Neurology

NYU Langone Health

UNITED STATES

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Sarah Mizielinska

King’s College London

UNITED KINGDOM

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Marjorie Metzger

Trinity College Dublin

IRELAND

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Alfredo Iacoangeli

King’s College London

UNITED KINGDOM

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Deirdre Murray

Associate Professor in Neurorehabilitation and Technology

Trinity College Dublin

IRELAND

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Adriano Chio

Professor of Neurology

University of Turin

ITALY

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Bernard Schneider

Senior Scientist

EPFL

SWITZERLAND

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Massimiliano Passaretti

Karolinska Institutet

SWEDEN

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Orla Hardiman

Research Interests

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Recent Grants

Articles (20)

Distinct Longitudinal Changes in EEG Measures Reflecting Functional Network Disruption in ALS Cognitive Phenotypes

A genetic perspective on the recent demographic history of Ireland and Britain

Oligogenic structure of amyotrophic lateral sclerosis has genetic testing, counselling and therapeutic implications

Clinical trajectories of genetic variants in ALS: a European observational study within PRECISION-ALS

Examining changing working status and caregiver assistance in amyotrophic lateral sclerosis (ALS) using large-scale European databases as part of PRECISION-ALS

Respiratory measurements, respiratory symptoms, and quality of life in ALS: results from the REVEALS study

Rate of change in upper and lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis

Real-world prognostic role of riluzole use in ALS: a multi-center study from PRECISION-ALS

Reldesemtiv in Amyotrophic Lateral Sclerosis

Challenges and solutions to complex data governance issues in cross-national, cross-sectoral, multidisciplinary real world health research: a descriptive overview

Clinical validation of a novel hand dexterity measurement device

Amyotrophic lateral sclerosis caused by hexanucleotide repeat expansions in C9orf72

Cerebellar dysfunction in frontotemporal dementia: intra-cerebellar pathology and cerebellar network degeneration

Abnormal EEG Spectral Power and Coherence Measures During Pre-Motor Stage in Amyotrophic Lateral Sclerosis

Pseudobulbar affect: clinical associations, social impact and quality of life implications - Lessons from PLS.

Mapping the natural history of amyotrophic lateral sclerosis: time-to-event analysis of clinical milestones in the pan-European, population-based PRECISION-ALS cohort

Natural history of the revised ALS functional rating scale and its association with survival: the PRECISION-ALS Extant Study

Progressive Thalamo-Cortical Disconnection in Amyotrophic Lateral Sclerosis Genotypes: Structural Degeneration and Network Dysfunction of Thalamus-Relayed Circuits

Respiratory function, survival, and NIV prevalence over time in ALS - a PRECISION ALS study

Epidemiologic Trends of Amyotrophic Lateral Sclerosis in Ireland, 1996–2021

Collaborators (27)

Dara Meldrum

Muthuraman Muthuraman

Edmund Gilbert

Philippe Couratier

Zachary Simmons

Ahmad Al Khleifat

David Schultz

Lara McManus

Peter Munch Andersen

Gianpiero Cavalleri

Russell McLaughlin

Roisin Mc Mackin

philippe corcia

Caroline Ingre

Johnathan Cooper‐Knock

Umberto Manera

Ammar Al-Chalabi

Peter Bede

Julian Großkreutz

Jinsy Andrews

Sarah Mizielinska

Marjorie Metzger

Alfredo Iacoangeli

Deirdre Murray

Adriano Chio

Bernard Schneider

Massimiliano Passaretti

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