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Russell McLaughlin

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Ussher Assistant Professor in Genome Analysis

Trinity College Dublin

Ireland

Research Interests

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About

Dr. Russell McLaughlin is an Ussher Assistant Professor in Genome Analysis at the University of Dublin Trinity College, Ireland. His research focuses on genetic insights into neurological disorders including amyotrophic lateral sclerosis and frontotemporal dementia, as well as demographic genetics related to Ireland and Britain. Dr. McLaughlin's recent publications emphasize the mapping of disease burden and genetic variations in neurodegenerative conditions, contributing to a better understanding of both clinical implications and potential therapeutic avenues.

Recent Grants

Grant: Close

Detecting the dark matter of neurodegeneration: repeat expansions in amyotrophic lateral sclerosis

Open Date: 2018-04-01

Close Date: 2022-03-01

Grant: Close

Advancing research in neurodegenerative disease: genome analysis in amyotrophic lateral sclerosis

Open Date: 2017-01-01

Close Date: 2019-01-01

Grant: Close

Junior Non-clinical Fellowship

Open Date: 2016-01-01

Close Date: 2018-12-01

Grant: Close

Use of extended Irish kindreds to identify novel ALS variants

Open Date: 2013-09-01

Close Date: 2015-08-01

Grant: Close

Milton Safenowitz Postdoctoral Fellowship

Open Date: 2013-08-01

Close Date: 2015-07-01

Articles (16)

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2026

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2021

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2021

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2021

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2020

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2020

Collaborators (28)

Edmund Gilbert

Lecturer

Royal College of Surgeons in Ireland

IRELAND

Russell McLaughlin

Research Interests

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About

Recent Grants

Articles (16)

Cognitive and behavioral manifestations of the C9orf72 mutation in Amyotrophic Lateral Sclerosis: an age, education, and gender-matched cohort study

Sex-aware causal inference assessment of the immune system in complex neurodegenerative diseases

Genetic ancestry and monogenic disease risk in the Scottish Traveller founder population

A genetic perspective on the recent demographic history of Ireland and Britain

Progressive Cerebrocerebellar Uncoupling in Sporadic and Genetic Forms of Amyotrophic Lateral Sclerosis

Cognitive and neuropsychiatric endophenotypes in amyotrophic lateral sclerosis

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis.

Mapping cortical disease-burden at individual-level in frontotemporal dementia: implications for clinical care and pharmacological trials.

Resting-state EEG reveals four subphenotypes of amyotrophic lateral sclerosis.

Genotype-associated cerebellar profiles in ALS: focal cerebellar pathology and cerebro-cerebellar connectivity alterations.

Infratentorial pathology in frontotemporal dementia: cerebellar grey and white matter alterations in FTD phenotypes.

REscan: inferring repeat expansions and structural variation in paired-end short read sequencing data.

Extra-motor cerebral changes and manifestations in primary lateral sclerosis.

Cross-reactive probes on Illumina DNA methylation arrays: a large study on ALS shows that a cautionary approach is warranted in interpreting epigenome-wide association studies.

Dutch population structure across space, time and GWAS design.

Collaborators (28)

Edmund Gilbert

Ashley Jones

Frank Baas

Marka van Blitterswijk

Sarah Opie-Martin

Jennifer Phillips-Cremins

MARTIN RICHARDS

Gianpiero Cavalleri

Bradley Smith

Roisin Mc Mackin

Sandra D'Alfonso

Paola Caroppo

Paolo Volanti

Sarah Gagliano Taliun

Michael Sendtner

Viviana Pensato

Danny Miller

simon topp

Kelly Williams

Lyle Ostrow

Garth Nicholson

Marcella Zollino

Marjorie Metzger

Stuart Pickering-Brown

Orla Hardiman

Caroline Vance

Oleg Butovsky

Francesca Brett

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