Pablo Huertas

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Universidad de Sevilla

Spain

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Relevance of double strand break repair pathway choice in human disease and cancer

Open Date: 2012-01-01

Close Date: 2016-12-01

Articles (16)

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Collaborators (10)

Peter van Veelen

Leiden University Medical Center

NETHERLANDS

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Sónia Silva

PORTUGAL

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Manuel Sanchez-Martin

Lecturer

Universidad de Salamanca

SPAIN

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María Luisa Moyá

Professor

Universidad de Sevilla

SPAIN

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Veronique A.J. Smits

Profesor asociado para programas de doctorado

Universidad Fernando Pessoa Canarias

SPAIN

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Néstor García Rodríguez

Assistant Professor

SPAIN

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Elena María Benito Hernández

Profesor Titular de Universidad

Universidad de Sevilla

SPAIN

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Fernando R. Balestra

Universidad de Sevilla

SPAIN

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Manuel López-López

Profesor Titular de Universidad

Universidad de Huelva

SPAIN

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Alessandro Sartori

University of Zurich

SWITZERLAND

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Pablo Huertas

Research Interests

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Recent Grants

Articles (16)

DNA topoisomerase IIß inhibition blocks DNA end resection and synergizes with PARPi in BRCA1-deficient models

EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis

PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection

A novel biocompatible polymer derived from D-mannitol used as a vector in the field of genetic engineering of eukaryotic cells

N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer

Centriolar subdistal appendages promote double‐strand break repair through homologous recombination

Multivalent Calixarene-Based Liposomes as Platforms for Gene and Drug Delivery

Cationic Single-Chained Surfactants with a Functional Group at the End of the Hydrophobic Tail DNA Compacting Efficiency

TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin

CtIP-mediated alternative mRNA splicing fine-tunes the DNA damage response

MRGBP, a member of the NuA4 complex, inhibits DNA double‐strand break repair

ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair

PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks

Preparation of a radiobiology beam line at the 18 MeV proton cyclotron facility at CNA

ALC1/eIF4A1-mediated regulation of CtIP mRNA stability controls DNA end resection

Collaborators (10)

Peter van Veelen

Sónia Silva

Manuel Sanchez-Martin

María Luisa Moyá

Veronique A.J. Smits

Néstor García Rodríguez

Elena María Benito Hernández

Fernando R. Balestra

Manuel López-López

Alessandro Sartori

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