Paola Gratteri

Associate Professor

University of Firenze

Italy

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Research Interests

Pharmaceutical Chemistry

100%

Organic Chemistry

50%

Chemical Biology

60%

Heterocyclic Chemistry

50%

Bioactive Compound

50%

Drug Development

40%

Molecular Modeling

40%

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Articles15

Synthesis, carbonic anhydrase inhibition studies and modelling investigations of phthalimide–hydantoin hybrids

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Year:

2024

Development of Penicillin-Based Carbonic Anhydrase Inhibitors Targeting Multidrug-Resistant Neisseria gonorrhoeae

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Year:

2024

Dual Inhibitors of Brain Carbonic Anhydrases and Monoamine Oxidase-B Efficiently Protect against Amyloid-β-Induced Neuronal Toxicity, Oxidative Stress, and Mitochondrial Dysfunction

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Year:

2024

Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains

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Year:

2024

Leveraging SARS-CoV-2 Main Protease (Mpro) for COVID-19 Mitigation with Selenium-Based Inhibitors

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Year:

2024

6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: <i>In Silico</i> Design, Synthesis, and X-ray Crystallography.

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Year:

2023

Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies

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Year:

2023

Pyrrolyl and Indolyl α-γ-Diketo Acid Derivatives Acting as Selective Inhibitors of Human Carbonic Anhydrases IX and XII

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Year:

2023

Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors

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Year:

2023

Inhibition Studies on Human and Mycobacterial Carbonic Anhydrases with N-((4-Sulfamoylphenyl)carbamothioyl) Amides

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Year:

2023

Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors

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Year:

2023

Inhibition Profiles of Some Novel Sulfonamide-Incorporated α-Aminophosphonates on Human Carbonic Anhydrases

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Year:

2023

Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors

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Year:

2023

Probing the Efficiency of 13-Pyridylalkyl Berberine Derivatives to Human Telomeric G-Quadruplexes Binding: Spectroscopic, Solid State and In Silico Analysis

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Year:

2022

Development of Hydrogen Sulfide-Releasing Carbonic Anhydrases IX- and XII-Selective Inhibitors with Enhanced Antihyperalgesic Action in a Rat Model of Arthritis

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Year:

2022

Collaborators17

Daniel Plano

Professor (Associate)

SPAIN

Jean-Yves WINUM

Professor

University of Montpellier

FRANCE

Roberto RONCA

University of Brescia

ITALY

Ashok Aspatwar

Adjunct Professor

FINLAND

Carmen Sanmartín

Universidad de Navarra

SPAIN

Tarita Biver

University of Pisa

ITALY

Óscar López

Associate Professor

Universidad de Sevilla

SPAIN

Carla Bazzicalupi

Prof. Dr.

University of Florence

ITALY

MATTEO SAVASTANO

Associate Professor - General & Inorganic Chemistry

Sapienza University of Rome

ITALY

Alessio Nocentini

University of Florence

ITALY

veronica papa

Assistant Professor

Università degli Studi di Napoli Parthenope

ITALY

Claudiu T Supuran

University of Florence

ITALY

Michael Smietana

FRANCE

luigi scipione

Associate Professor

Università degli Studi di Roma La Sapienza

ITALY

Seppo Parkkila

University of Tampere

FINLAND

Andrea Angeli

University of Florence

ITALY

Valentina Noemi Madia

Sapienza University of Rome

ITALY

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