Paola Gratteri

Associate Professor

University of Firenze

Italy

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Paola Gratteri is an Associate Professor at the University of Firenze, Italy. Her research primarily focuses on the design and synthesis of inhibitors for human carbonic anhydrases, contributing to advancements in therapeutic approaches for various diseases. Recent articles highlight her work on aromatic hydrazides, dual-tail pyrrol-2-ones, and polypharmacological therapies, reflecting her commitment to addressing complex biochemical challenges.

Articles (20)

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2025

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2022

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2022

Collaborators (22)

José M. Padrón

Full Professor

Universidad de la Laguna

SPAIN

Paola Gratteri

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Articles (20)

Exploration of Aromatic Hydrazides as Inhibitors of Human Carbonic Anhydrases

Novel 3-Sulfonamide Dual-Tail Pyrrol-2-one Bridged Molecules as Potent Human Carbonic Anhydrase Isoform Inhibitors: Design, Synthesis, Molecular Modeling Investigation, and Anticancer Activity in MeWo, SK-BR-3, and MG-63 Cell Lines

Synthesis, carbonic anhydrase inhibition studies and modelling investigations of phthalimide–hydantoin hybrids

Development of Penicillin-Based Carbonic Anhydrase Inhibitors Targeting Multidrug-Resistant Neisseria gonorrhoeae

Dual Inhibitors of Brain Carbonic Anhydrases and Monoamine Oxidase-B Efficiently Protect against Amyloid-β-Induced Neuronal Toxicity, Oxidative Stress, and Mitochondrial Dysfunction

Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains

Leveraging SARS-CoV-2 Main Protease (Mpro) for COVID-19 Mitigation with Selenium-Based Inhibitors

Exploring the Polypharmacological Potential of PCI-27483: A Selective Inhibitor of Carbonic Anhydrases IX and XII

Synthesis and investigation of selective human carbonic anhydrase IX, XII inhibitors using coumarins bearing a sulfonamide or biotin moiety

Superacid-Synthesized Fluorinated Diamines Act as Selective hCA IV Inhibitors

6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: <i>In Silico</i> Design, Synthesis, and X-ray Crystallography.

Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies

Pyrrolyl and Indolyl α-γ-Diketo Acid Derivatives Acting as Selective Inhibitors of Human Carbonic Anhydrases IX and XII

Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors

Inhibition Studies on Human and Mycobacterial Carbonic Anhydrases with N-((4-Sulfamoylphenyl)carbamothioyl) Amides

Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors

Inhibition Profiles of Some Novel Sulfonamide-Incorporated α-Aminophosphonates on Human Carbonic Anhydrases

Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors

Probing the Efficiency of 13-Pyridylalkyl Berberine Derivatives to Human Telomeric G-Quadruplexes Binding: Spectroscopic, Solid State and In Silico Analysis

Development of Hydrogen Sulfide-Releasing Carbonic Anhydrases IX- and XII-Selective Inhibitors with Enhanced Antihyperalgesic Action in a Rat Model of Arthritis

Collaborators (22)

José M. Padrón

Roberto Di Santo

Daniel Plano

Jean-Yves WINUM

Roberto RONCA

Ashok Aspatwar

Carmen Sanmartín

Tarita Biver

Óscar López

Carla Bazzicalupi

MATTEO SAVASTANO

Alessio Nocentini

veronica papa

Claudiu T Supuran

Michael Smietana

luigi scipione

Marta Ferraroni

Seppo Parkkila

Andrea Angeli

Gianluca Bartolucci

Susanna Scarpa

Valentina Noemi Madia

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