Patrick Collins

Research Assistant Professor

Ohio State University

United States

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Patrick Collins is a Research Assistant Professor at The Ohio State University, USA. His research focuses on transcriptional regulation, immune cell responses, and the molecular mechanisms underlying various immune-related conditions. Recent publications highlight his work on thymocyte development, multiple sclerosis models, and the regulation of T cell responses. Through his studies, he aims to elucidate the regulatory circuits in innate and adaptive immune cells.

Articles (12)

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2025

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2020

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2020

Collaborators (9)

Kevin Cho

Washington University in St. Louis

UNITED STATES

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Jonathan Brestoff

Assistant Professor

Washington University School of Medicine

UNITED STATES

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Hyung Joo Lee

UNITED STATES

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Marina Cella

Associate Professor

Washington University in St. Louis

UNITED STATES

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Melissa Leonard

Ohio State University

UNITED STATES

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Hazem Ghoneim

Assistant Professor

The Ohio State University College of Medicine

UNITED STATES

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Bethany Mundy-Bosse

Associate Professor

Ohio State University

UNITED STATES

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Jacob Yount

Associate Professor

Ohio State University

UNITED STATES

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Daofeng Li

Assistant Professor

Washington University in St. Louis

UNITED STATES

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Patrick Collins

Research Interests

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Articles (12)

Transcriptional regulation of Ligase IV by an intronic regulatory element directs thymocyte development

The transcription factor Aiolos restrains the activation of intestinal intraepithelial lymphocytes

Cytotoxic Programming of CD4+ T Cells Is Regulated by Opposing Actions of the Related Transcription Factors Eos and Aiolos.

Novel model of multiple sclerosis induced by EBV-like virus generates a unique B cell population.

Neutrophil-mediated hypoxia drives pathogenic CD8+ T cell responses in cutaneous leishmaniasis.

Deletion of Glycogen Synthase Kinase 3 Beta Reprograms NK Cell Metabolism

BAP1 promotes osteoclast function by metabolic reprogramming

Aiolos represses CD4<sup>+</sup> T cell cytotoxic programming via reciprocal regulation of T<sub>FH</sub> transcription factors and IL-2 sensitivity.

Whole-genome profiling of DNA methylation and hydroxymethylation identifies distinct regulatory programs among innate lymphocytes

Gene Regulatory Circuits in Innate and Adaptive Immune Cells.

Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis

DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner

Collaborators (9)

Kevin Cho

Jonathan Brestoff

Hyung Joo Lee

Marina Cella

Melissa Leonard

Hazem Ghoneim

Bethany Mundy-Bosse

Jacob Yount

Daofeng Li

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