paul de vos

Professor

University Medical Center Groningen

Netherlands

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Paul de Vos is a Professor at the University Medical Center Groningen in the Netherlands. His research focuses on gut health, particularly the interactions of dietary components and gut microbiota, as highlighted in his recent articles. Key areas of study include the protective effects of pectins and human milk oligosaccharides on gut barrier integrity, as well as the modulation of immune responses by exopolysaccharides from various bacterial species.

Articles (20)

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2025

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2023

Collaborators (9)

Marcel Karperien

University of Twente

NETHERLANDS

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Luis Silva

University Medical Center Groningen

NETHERLANDS

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Malin Becker

University of Twente

NETHERLANDS

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Marthe Walvoort

Professor at University of Groningen

University of Groningen

NETHERLANDS

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Michela Ferrari

University of Groningen

NETHERLANDS

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Jeroen Leijten

Prof. dr. at University of Twente

University of Twente

NETHERLANDS

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Yuxin Wang

Rijksuniversiteit Groningen Faculty of Science and Engineering

NETHERLANDS

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Edita Jurak

Assistant Professor

University of Groningen

NETHERLANDS

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Henk A. Schols

Wageningen University & Research

NETHERLANDS

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paul de vos

Research Interests

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Articles (20)

Impact of GOS and 2’-FL on the production and structural composition of membrane-associated exopolysaccharides by B. adolescentis and B. infantis

Pectins mitigate Candidalysin-induced gut barrier disruption and inflammation in vitro in a degree of methyl-esterification-dependent manner

Exopolysaccharides from Bifidobacterium longum supsp. Infantis and Bifidobacterium adolescentis protect gut epithelial cells from antibiotic- induced disruption but do not affect epithelial responses to Escherichia Coli

Protective Effects of Human Milk Oligosaccharides (hMOs) on Analgesic, Nonsteroidal Anti-inflammatory Drugs (NSAIDs)-Induced Disruption of Gut Barrier Integrity in Cocultures Mimicking Neuro-Gut Epithelial Cell Crosstalk

Lactobacillus plantarum in high methoxylated pectin-based encapsulation systems supports gut epithelial wound healing in vitro

Polymerized laminin-modified microcapsules improve pancreatic islet resilience towards cytokine induced inflammatory stress and lower chemoattractant cytokine secretion

Swine Gut Lactic Acid Bacteria and Their Exopolysaccharides Differentially Modulate Toll-like Receptor Signaling Depending on the Agave Fructans Used as a Carbon Source

Pectin-based encapsulation systems for the protection of beneficial bacterial species and impact on intestinal barrier function in vitro

Immunostimulatory effects of isomalto/malto-polysaccharides via TLR2 and TLR4 in preventing doxycycline-induced cytokine loss

Exopolysaccharides from Bifidobacterium longum subsp. infantis and Bifidobacterium adolescentis modulate Toll-like receptor signaling

Microfluidic Generation of Thin‐Shelled Polyethylene Glycol‐Tyramine Microgels for Non‐Invasive Delivery of Immunoprotected β‐Cells

β(2 → 1)-β(2 → 6) and β(2 → 1) fructans protect from impairment of intestinal tight junction's gene expression and attenuate human dendritic cell responses in a fructan-dependent fashion

Type of intrinsic resistant starch type 3 determines in vitro fermentation by pooled adult faecal inoculum

Enhancing longevity of immunoisolated pancreatic islet grafts by modifying both the intracapsular and extracapsular environment

Effects of thermal treatments on the extraction and in vitro fermentation patterns of pectins from pomelo (Citrus grandis)

Unveiling Plant-Based Pectins: Exploring the Interplay of Direct Effects, Fermentation, and Technological Applications in Clinical Research with a Focus on the Chemical Structure

Efficacy of pectins with different degrees of methyl-esterification and of blockiness in preventing gut epithelial cell barrier disruption and the impact on sodium-glucose co-transporter expression under low and high glucose conditions

Structure-function relationship and impact on the gut-immune barrier function of non-digestible carbohydrates and human milk oligosaccharides applicable for infant formula

Extracellular matrix inclusion in immunoisolating alginate-based microcapsules promotes longevity, reduces fibrosis, and supports function of islet allografts in vivo

TLR 2/1 interaction of pectin depends on its chemical structure and conformation

Collaborators (9)

Marcel Karperien

Luis Silva

Malin Becker

Marthe Walvoort

Michela Ferrari

Jeroen Leijten

Yuxin Wang

Edita Jurak

Henk A. Schols

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