Pavla Fajtová

Institute of Organic Chemistry and Biochemistry

Czech Republic

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Articles (20)

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2025

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2024

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2022

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2022

Collaborators (6)

Daniel Petras

University of Tuebingen

GERMANY

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Mark Larance

Senior Lecturer

University of Sydney

AUSTRALIA

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Jair Siqueira-Neto

Assistant Professor

University of California, San Diego

UNITED STATES

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Khaled A. Selim

Jun. Professor

University of Freiburg

GERMANY

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Wout Bittremieux

University of Antwerp

BELGIUM

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Anthony O'Donoghue

Associate Professor

University of California, San Diego

UNITED STATES

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Pavla Fajtová

Research Interests

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Articles (20)

A multiplex method for rapidly identifying viral protease inhibitors

Structural insights into Salinosporamide A mediated inhibition of the human 20S proteasome

Development of subunit selective proteasome substrates for Schistosoma species

Distinct substrate specificities of the three catalytic subunits of the <i>Trichomonas vaginalis</i> proteasome

Evaluating Antimalarial Proteasome Inhibitors for Efficacy in <i>Babesia</i> Blood Stage Cultures

Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis

Structural elucidation of recombinant <i>Trichomonas vaginalis</i> 20S proteasome bound to covalent inhibitors

Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors

Development of subunit selective substrates for Trichomonas vaginalis proteasome

Empirical Optimization of Peptide Sequence and Nanoparticle Colloidal Stability: The Impact of Surface Ligands and Implications for Colorimetric Sensing

Native metabolomics identifies the rivulariapeptolide family of protease inhibitors

Discovery of Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L

A Charge-Switchable Zwitterionic Peptide for Rapid Detection of SARS-CoV-2 Main Protease

A Dual-Color Fluorescent Probe Allows Simultaneous Imaging of Main and Papain-like Proteases of SARS-CoV-2-Infected Cells for Accurate Detection and Rapid Inhibitor Screening

A Self-Immolative Fluorescent Probe for Selective Detection of SARS-CoV-2 Main Protease

Peptidic Sulfhydryl for Interfacing Nanocrystals and Subsequent Sensing of SARS-CoV-2 Protease

Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L

Protease-Responsive Peptide-Conjugated Mitochondrial-Targeting AIEgens for Selective Imaging and Inhibition of SARS-CoV-2-Infected Cells

Spacer Matters: All-Peptide-Based Ligand for Promoting Interfacial Proteolysis and Plasmonic Coupling

Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease M<sup>pro</sup>and Papain-like Protease PL<sup>pro</sup>of SARS-CoV-2

Collaborators (6)

Daniel Petras

Mark Larance

Jair Siqueira-Neto

Khaled A. Selim

Wout Bittremieux

Anthony O'Donoghue

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