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Peter Fineran

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Professor

University of Otago

New Zealand

Research Interests

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About

Professor Peter Fineran is a faculty member at the University of Otago, New Zealand. His research focuses on phage-bacterial interactions, CRISPR-Cas systems, and the ecological impact of bacteriophages in various environments. Recent publications include investigations into phage resistance, genomic influences on bacterial immunity, and innovative approaches to biocontrol strategies.

Recent Grants

Grant: Open

Bacterial defences that block jumbo phages

Open Date: 2026-01-01

Close Date: 2029-01-01

Grant: Open

Understanding bacteriophage-pathogen specificity to support phage therapy.

Open Date: 2024-01-01

Close Date: 2027-01-01

Grant: Close

A high-throughput mutagenesis method to identify essential phage genes and introduce genetic cargo

Open Date: 2024-01-01

Close Date: 2026-01-01

Grant: Open

Adaptable phage solutions: an Aotearoa-NZ platform for precision biocontrol for primary industries

Open Date: 2023-10-01

Close Date: 2028-09-30

Grant: Close

Enhancing seed inoculants with bacteriophages to enable more sustainable agriculture

Open Date: 2021-10-01

Close Date: 2025-03-31

Articles (32)

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Collaborators (27)

Chris M Brown

University of Otago

NEW ZEALAND

Peter Fineran

Research Interests

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About

Recent Grants

Articles (32)

Defining the essential genome of diverse phages with phage Tn-seq

An expanded realm of anti-CRISPR-associated proteins and regulatory mechanisms

Genome scale CRISPRi reveals both shared and strain-specific vulnerabilities in genetically diverse drug-resistant strains of Mycobacterium tuberculosis

The early injected genomic region determines sensitivity to Type I restriction-modification defence against Autographiviridae phages

Abiotic environmental conditions determine phage resistance outcomes in a salt-marsh bacterium

Phage defence-system abundances vary across environments and increase with viral density

Type I CRISPR-Cas immunity primes type III spacer acquisition

CRISPR2025 New Zealand: Innovation and Collaboration

Global structural survey of the flagellotropic myophage φTE infecting agricultural pathogen Pectobacterium atrosepticum

Genome-wide identification of bacterial genes contributing to nucleus-forming jumbo phage infection

Towards a phylogenetically informed approach to solving protein–protein interactions

Regulation of anti-CRISPR operons by structurally distinct families of Aca proteins

Antibacterial synergy between a phage endolysin and citric acid against the Gram-negative kiwifruit pathogen Pseudomonas syringae pv. actinidiae

RNA targeting and cleavage by the type III-Dv CRISPR effector complex.

Serratia‐based toxin cluster elements are associated with a type I fimbria

Inhibitors of bacterial immune systems: discovery, mechanisms and applications

CRISPR-Cas immunity is repressed by the LysR-type transcriptional regulator PigU

Strategies for the biocontrol Pseudomonas infections pre‐fruit harvest

Repurposing an Endogenous CRISPR-Cas System to Generate and Study Subtle Mutations in Bacteriophages

Approaches for bacteriophage genome engineering

The biology and type I/III hybrid nature of type I-D CRISPR–Cas systems

An OmpW-dependent T4-like phage infects Serratia sp. ATCC 39006

Genome sequences of Mx1, the first Myxococcus phage isolated, and Mx4, a generalized transducing myxophage

Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs

Identification of Streptococcus pneumoniae genes associated with hypothiocyanous acid tolerance through genome-wide screening

CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids

Structural rearrangements allow nucleic acid discrimination by type I-D Cascade

Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection

Molecular basis of dual anti-CRISPR and auto-regulatory functions of AcrIF24

Molecular basis of anti-CRISPR operon repression by Aca10

Widespread repression of anti-CRISPR production by anti-CRISPR-associated proteins

PADLOC: a web server for the identification of antiviral defence systems in microbial genomes

Collaborators (27)

Chris M Brown

David Taylor

Ghader Bashiri

Chase Beisel

Nina Dickerhof

Antonio Sanchez-Amat

Joseph Nesme

Robert D. Fagerlund

Dipali Sashital

Nicolas Toro

Montserrat Elías-Arnanz

Mihnea Bostina

Mark Hurst

Simon A Jackson

Mark Hampton

Stan J. J. Brouns

Jonas Stenløkke Madsen

Gavin J. Knott

Paul Gardner

Patricia Elío Lucas

Suzanne Warring

Travis Glare

Murray Cox

Peter Mace

Giulia Palermo

Saadlee Shehreen

Jack Bravo

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