Peter Fineran

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Professor

University of Otago

New Zealand

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Professor Peter Fineran is a faculty member at the University of Otago, New Zealand. His research focuses on phage-bacterial interactions, CRISPR-Cas systems, and the ecological impact of bacteriophages in various environments. Recent publications include investigations into phage resistance, genomic influences on bacterial immunity, and innovative approaches to biocontrol strategies.

Recent Grants

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How do bacterial CRISPR-Cas defences protect against nucleus-forming phages?

Open Date: 2021-01-01

Close Date: 2024-01-01

Grant: Close

Are molecular mis-interactions a major constraint on the evolution of cellular and genomic complexity?

Open Date: 2020-01-01

Close Date: 2023-01-01

Grant: Close

Uncovering regulatory networks controlling CRISPR-Cas adaptive immunity

Open Date: 2018-01-01

Close Date: 2021-01-01

Grant: Close

How do bacterial ‘adaptive immune systems’ protect microbial cells against viral infection?

Open Date: 2012-01-01

Close Date: 2017-01-01

Peter Fineran

Research Interests

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Recent Grants

Articles (27)

The early injected genomic region determines sensitivity to Type I restriction-modification defence against Autographiviridae phages

Abiotic environmental conditions determine phage resistance outcomes in a salt-marsh bacterium

Phage defence-system abundances vary across environments and increase with viral density

Type I CRISPR-Cas immunity primes type III spacer acquisition

CRISPR2025 New Zealand: Innovation and Collaboration

Global structural survey of the flagellotropic myophage φTE infecting agricultural pathogen Pectobacterium atrosepticum

Genome-wide identification of bacterial genes contributing to nucleus-forming jumbo phage infection

Antibacterial synergy between a phage endolysin and citric acid against the Gram-negative kiwifruit pathogen Pseudomonas syringae pv. actinidiae

RNA targeting and cleavage by the type III-Dv CRISPR effector complex.

Serratia‐based toxin cluster elements are associated with a type I fimbria

Inhibitors of bacterial immune systems: discovery, mechanisms and applications

CRISPR-Cas immunity is repressed by the LysR-type transcriptional regulator PigU

Strategies for the biocontrol Pseudomonas infections pre‐fruit harvest

Repurposing an Endogenous CRISPR-Cas System to Generate and Study Subtle Mutations in Bacteriophages

Approaches for bacteriophage genome engineering

The biology and type I/III hybrid nature of type I-D CRISPR–Cas systems

An OmpW-dependent T4-like phage infects Serratia sp. ATCC 39006

Genome sequences of Mx1, the first Myxococcus phage isolated, and Mx4, a generalized transducing myxophage

Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs

Identification of Streptococcus pneumoniae genes associated with hypothiocyanous acid tolerance through genome-wide screening

CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids

Structural rearrangements allow nucleic acid discrimination by type I-D Cascade

Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection

Molecular basis of dual anti-CRISPR and auto-regulatory functions of AcrIF24

Molecular basis of anti-CRISPR operon repression by Aca10

Widespread repression of anti-CRISPR production by anti-CRISPR-associated proteins

PADLOC: a web server for the identification of antiviral defence systems in microbial genomes

Collaborators (21)

Chris M Brown

David Taylor

Nina Dickerhof

Antonio Sanchez-Amat

Joseph Nesme

Robert D. Fagerlund

Nicolas Toro

Montserrat Elías-Arnanz

Mark Hurst

Simon A Jackson

Mark Hampton

Stan J. J. Brouns

Jonas Stenløkke Madsen

Paul Gardner

Patricia Elío Lucas

Suzanne Warring

Travis Glare

Murray Cox

Giulia Palermo

Saadlee Shehreen

Jack Bravo

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