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Petr Man

Institute of Microbiology

Czech Republic

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Research Interests

Biochemistry

100%

Cell Biology

40%

Protein Chemistry

50%

Chemical Biology

50%

Enzymology

30%

Membrane Biology

30%

Mutagenesis

30%

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Articles13

Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants

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Year:

2024

Structural dynamics of Na<sup>+</sup> and Ca<sup>2+</sup> interactions with full-size mammalian NCX.

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Year:

2024

Chloride intracellular channel (CLIC) proteins function as fusogens

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Year:

2024

Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease‐associated NQO1 enzyme*

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Year:

2023

A conserved tryptophan in the acylated segment of RTX toxins controls their β2 integrin–independent cell penetration

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Year:

2023

Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations

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Year:

2022

A single evolutionarily divergent mutation determines the different FAD‐binding affinities of human and rat NQO1 due to site‐specific phosphorylation

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Year:

2022

TTYH family members form tetrameric complexes at the cell membrane

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Year:

2022

Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core

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Year:

2022

Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

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Year:

2022

Structural basis for long-chain isoprenoid synthesis by cis-prenyltransferases

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Year:

2022

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

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Year:

2021

Functional expression and characterization of two laccases from the brown rot Fomitopsis pinicola

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Year:

2021

Collaborators11

Yoni Haitin

ISRAEL

Zuzana Kalaninová

Přírodovědecká Fakulta, Univerzita Karlova

CZECH REPUBLIC

Radim Osicka

Czech Academy of Sciences, Institute of Microbiology

CZECH REPUBLIC

Rita Guzzi

Professore associato

University of Calabria

ITALY

Rogelio Palomino-Morales

Assistant Professor

Universidad de Granada

SPAIN

José L. Neira

Universidad de Zaragoza

SPAIN

Eduardo Salido

Professor and Chair

Hospital Universitario de Canarias

SPAIN

Milagros Medina

Universidad de Zaragoza

SPAIN

Dmitry Loginov

CZECH REPUBLIC

Angel Luis Pey

Assistant Professor

Universidad de Granada

SPAIN

Lukáš Fojtík

Charles University

CZECH REPUBLIC

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