Philip Humphreys

GlaxoSmithKline

United Kingdom

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Articles (7)

Year:

2023

Year:

2022

Year:

2022

Year:

2020

Year:

2020

Year:

2020

Year:

2020

Collaborators (4)

Natalie Theodoulou

University of Manchester

UNITED KINGDOM

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Rosa Ellen Cookson

Tessera Therapeutics

UNITED KINGDOM

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Marc Reid

University Of Strathclyde

UNITED KINGDOM

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Craig Jamieson

Professor

University Of Strathclyde

UNITED KINGDOM

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Philip Humphreys

Research Interests

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Articles (7)

Structure-guided design of a domain-selective bromodomain and extra terminal N-terminal bromodomain chemical probe

Identification and optimization of a ligand-efficient benzoazepinone bromodomain and extra terminal (BET) family acetyl-lysine mimetic into the oral candidate quality molecule I-BET432

Design, Synthesis, and Characterization of I-BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate

Alkene Syn- And Anti-Oxyamination with Malonoyl Peroxides

Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains

Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening

Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma cruzi

Collaborators (4)

Natalie Theodoulou

Rosa Ellen Cookson

Marc Reid

Craig Jamieson

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