Piroska Szabó

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Van Andel Institute

United States

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Recent Grants

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A NOVEL PROCESS SAFEGUARDS GENOME INTEGRITY IN THE MAMMALIAN GERM LINE

Open Date: 2022-06-01

Close Date: 2026-05-01

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Epigenetic effects of endocrine disruptors in fetal germ cells

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Mechanism of genomic imprinting

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Articles (12)

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

Year:

2021

Collaborators (3)

Gerd Pfeifer

Van Andel Institute

UNITED STATES

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Wanding Zhou

Assistant Professor

Children's Hospital of Philadelphia

UNITED STATES

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Purnima Singh

Associate Professor

The University of Alabama

UNITED STATES

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Piroska Szabó

Research Interests

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Recent Grants

Articles (12)

Role of Transcription in Imprint Establishment in the Male and Female Germ Lines

The link between 5-hydroxymethylcytosine and DNA demethylation in early embryos

Establishment of paternal methylation imprint at the H19/Igf2 imprinting control region

Concordance of hydrogen peroxide–induced 8-oxo-guanine patterns with two cancer mutation signatures of upper GI tract tumors

Z-DNA is remodelled by ZBTB43 in prospermatogonia to safeguard the germline genome and epigenome.

DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse

The remodeling of Z-DNA in the mammalian germ line.

EHMT2 suppresses the variation of transcriptional switches in the mouse embryo.

H3K9 methyltransferase EHMT2/G9a controls ERVK-driven noncanonical imprinted genes

Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes.

High-Resolution Analysis of 5-Hydroxymethylcytosine by TET-Assisted Bisulfite Sequencing.

Immunochemical Detection of Modified Cytosine Species in Mammalian Preimplantation Embryos.

Collaborators (3)

Gerd Pfeifer

Wanding Zhou

Purnima Singh

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