Wanding Zhou

Assistant Professor

Children's Hospital of Philadelphia

United States

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Wanding Zhou is an Assistant Professor at the Children's Hospital of Philadelphia, USA. His research focuses on DNA methylation, epigenetics, and computational methods for single-cell analysis, as evidenced by his recent articles on topics such as spatial joint profiling and ecological impacts on epigenetic aging. He is also involved in developing tools for harmonizing methylation data and improving detection methodologies through advanced signal processing and deep learning techniques.

Articles (20)

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2025

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2020

Collaborators (8)

Jason Farrar

Assistant Professor

University of Arkansas for Medical Sciences

UNITED STATES

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Hui Shen

Van Andel Institute

UNITED STATES

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Purnima Singh

Associate Professor

The University of Alabama

UNITED STATES

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Piroska Szabó

Van Andel Institute

UNITED STATES

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Xiaotian Zhang

Assistant Professor

The University of Texas Health Science Center at Houston

UNITED STATES

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Hitoshi Ohtani

Assistant Professor

Nagoya University

JAPAN

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Linn Gillberg

DENMARK

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PETER W LAIRD

Van Andel Institute

UNITED STATES

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Wanding Zhou

Research Interests

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About

Articles (20)

Spatial joint profiling of DNA methylome and transcriptome in tissues

Ecological Realism Accelerates Epigenetic Aging in Mice

On correlative and causal links of replicative epimutations

BISCUIT: an efficient, standards-compliant tool suite for simultaneous genetic and epigenetic inference in bulk and single-cell studies.

mLiftOver: harmonizing data across Infinium DNA methylation platforms

Low-input and single-cell methods for Infinium DNA methylation BeadChips

A signal processing and deep learning framework for methylation detection using Oxford Nanopore sequencing

Dupsifter: a lightweight duplicate marking tool for whole genome bisulfite sequencing.

Computational Methods for Single-Cell DNA Methylome Analysis

Comparative epigenome analysis using Infinium DNA methylation BeadChips

A mammalian methylation array for profiling methylation levels at conserved sequences.

A B-cell developmental gene regulatory network is activated in infant AML.

EHMT2 suppresses the variation of transcriptional switches in the mouse embryo.

Host methylation predicts SARS-CoV-2 infection and clinical outcome.

Analytical protocol to identify local ancestry-associated molecular features in cancer.

Evaluation of whole-genome DNA methylation sequencing library preparation protocols.

Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer.

Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity

DNA methylation enables transposable element-driven genome expansion.

Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine.

Collaborators (8)

Jason Farrar

Hui Shen

Purnima Singh

Piroska Szabó

Xiaotian Zhang

Hitoshi Ohtani

Linn Gillberg

PETER W LAIRD

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