Piyoosh Sharma

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Research Assistant Professor

Washington University in St. Louis

United States

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Dr. Piyoosh Sharma is a Research Assistant Professor at Washington University in St. Louis, USA. His research areas include protein misfolding, drug design strategies, and protein structural perturbations, as evidenced by his recent articles. He has explored various aspects of protein interactions and their implications for diseases such as Alzheimer's, utilizing computational methods and experimental validations.

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Young Scientist in newer areas of Drugs Chemistry

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Articles (10)

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2025

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2025

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2024

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2023

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2023

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2022

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2022

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2020

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2020

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2020

Collaborators (3)

Yingzi Xia

Johns Hopkins University

UNITED STATES

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Ian Sitarik

Pennsylvania State University

UNITED STATES

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Stephen Fried

Assistant Professor

Johns Hopkins University

UNITED STATES

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Piyoosh Sharma

Research Interests

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Recent Grants

Articles (10)

Non-native entanglement protein misfolding observed in all-atom simulations and supported by experimental structural ensembles

Protein misfolding involving entanglements provides a structural explanation for the origin of stretched-exponential refolding kinetics

Proteome-Wide Assessment of Protein Structural Perturbations under High Pressure

Progress toward Proteome-Wide Photo-Cross-Linking to Enable Residue-Level Visualization of Protein Structures and Networks In Vivo

Hydroxamic acid derivatives as selective HDAC3 inhibitors: computer-aided drug design strategies

Proteome-Wide Photo-Crosslinking Enables Residue-Level Visualization of Protein Interaction Networks <i>in vivo</i>

A New Class of Protein Misfolding is Observed in All-atom Folding Simulations

Cholinesterase as a Target for Drug Development in Alzheimer's Disease

Computational exploration and experimental validation to identify a dual inhibitor of cholinesterase and amyloid-beta for the treatment of Alzheimer’s disease

Computational Exploration and Experimental Validation to Identify a Dual Inhibitor of Cholinesterase and Amyloid-beta for the Treatment of Alzheimer’s Disease

Collaborators (3)

Yingzi Xia

Ian Sitarik

Stephen Fried

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