Prof T Graham

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This PhD project at the Institute of Cancer Research focuses on developing innovative methodologies to infer tumour dynamics by analyzing genomic and methylation changes in cell-free DNA (cfDNA) obtained from blood samples of cancer patients. The research aims to advance the understanding of cancer progression and response to treatment by leveraging non-invasive liquid biopsy techniques. Students will work at the intersection of cancer genomics, epigenetics, and biomarker discovery, utilizing cutting-edge molecular biology and computational approaches. The project is ideal for candidates interested in cancer biology, molecular diagnostics, and translational research. The position offers the opportunity to contribute to impactful cancer research in a leading UK institution. Details regarding funding, eligibility, and application procedures are not specified in the provided description.

This PhD project at the Institute of Cancer Research focuses on understanding the evolution of resistance to cancer therapies, a major challenge in oncology. Drug resistance enables cancer cells to survive treatment, but often results in a proliferative cost, slowing down cell division. The research aims to investigate the mechanisms by which cancer cells adapt to therapeutic pressures and the biological consequences of resistance, with the goal of informing future strategies to overcome or prevent resistance in clinical settings. The project is ideal for candidates interested in cancer biology, cellular adaptation, and therapeutic resistance. Details about funding, eligibility, and application procedures are not provided in the current description.