Qing Jun Meng

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The University of Manchester

United Kingdom

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Opportunities to modulate extracellular matrix secretion and assembly for long term health

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Targeting circadian rhythms to slow down the degeneration of the intervertebral disc

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Circadian clocks and Osteoarthritis

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Articles (19)

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2025

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2020

Collaborators (18)

Thomas House

The University of Manchester

UNITED KINGDOM

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Michael Harvey Hastings

Programme Leader (former Head of Division, 2013- 2023)

MRC Laboratory of Molecular Biology

UNITED KINGDOM

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Rachel Lennon

The University of Manchester

UNITED KINGDOM

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Joseph Chambers

Assistant Research Professor

University of Cambridge

UNITED KINGDOM

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Karl Kadler

The University of Manchester

UNITED KINGDOM

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Nan Yang

University of Oxford

UNITED KINGDOM

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Neil Humphreys

Head of Gene Editing and Embryology Facility

ITALY

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Benjamin Faber

University of Bristol

UNITED KINGDOM

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Steven Woods

The University of Manchester

UNITED KINGDOM

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Andrew Loudon

The University of Manchester

UNITED KINGDOM

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Nicola Bates

The University of Manchester

UNITED KINGDOM

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Ching-Yan Chloé Yeung

Faculty of Health and Medical Sciences, University of Copenhagen

DENMARK

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Egor Zindy

Université libre de Bruxelles (ULB)

BELGIUM

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Robert Clarke

The University of Manchester

UNITED KINGDOM

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REBECCA VOORHEES

Assistant Professor

California Institute of Technology

UNITED STATES

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Antony Adamson

The University of Manchester

UNITED KINGDOM

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Mark Naven

University of Bristol

UNITED KINGDOM

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Erik Herzog

Washington University

UNITED STATES

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Qing Jun Meng

Research Interests

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Recent Grants

Articles (19)

Quantitative measures of clock protein dynamics in the mouse suprachiasmatic nucleus extends the circadian time-keeping model

Associations between work characteristics and osteoarthritis: A cross-sectional study of 285,947 UK Biobank participants

A synthetic chronogenetic gene circuit for programmed circadian drug delivery

Can we utilise the circadian clock to target cancer stem cells?

The glomerular circadian clock temporally regulates basement membrane dynamics and the podocyte glucocorticoid response

Tumor circadian clock strength influences metastatic potential and predicts patient prognosis in luminal A breast cancer

Meteorin-like protein/METRNL/Interleukin-41 ameliorates atopic dermatitis-like inflammation

Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors.

The clock transcription factor BMAL1 is a key regulator of extracellular matrix homeostasis and cell fate in the intervertebral disc

The circadian clock and extracellular matrix homeostasis in ageing and age-related diseases

Mmp14 is required for matrisome homeostasis and circadian rhythm in fibroblasts

Macromolecular condensation buffers intracellular water potential.

Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock

Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model.

Synthetic gene circuits for preventing disruption of the circadian clock due to interleukin-1–induced inflammation

The dynamic kidney matrisome - is the circadian clock in control?

Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration

Tissue physiology revolving around the clock: circadian rhythms as exemplified by the intervertebral disc

Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator

Collaborators (18)

Thomas House

Michael Harvey Hastings

Rachel Lennon

Joseph Chambers

Karl Kadler

Nan Yang

Neil Humphreys

Benjamin Faber

Steven Woods

Andrew Loudon

Nicola Bates

Ching-Yan Chloé Yeung

Egor Zindy

Robert Clarke

REBECCA VOORHEES

Antony Adamson

Mark Naven

Erik Herzog

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