Rachel McCord

Associate Professor

The University of Tennessee Knoxville

United States

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Dr. Rachel McCord is an Associate Professor at The University of Tennessee Knoxville, United States. Her research focuses on cellular dynamics and gene regulation, as evidenced by her recent publications exploring 3D genome architecture in melanoma migration, heterochromatin's role in gene expression, and the effects of nuclear lamina association on gene regulation. Additionally, she investigates the implications of chromosome conformation and DNA repair mechanisms in the context of radio-sensitivity and cancer biology.

Articles (15)

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2025

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2022

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2022

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UNITED STATES

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Rachel McCord

Research Interests

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Articles (15)

Polymer model integrates imaging and sequencing to reveal how nanoscale heterochromatin domains influence gene expression

Deciphering pre-existing and induced 3D genome architecture changes involved in constricted melanoma migration

Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer

Chromosome compartmentalization: causes, changes, consequences, and conundrums

Integrating chromosome conformation and DNA repair in a computational framework to assess cell radiosensitivity.

Differential contributions of nuclear lamina association and genome compartmentalization to gene regulation

MASI enables fast model-free standardization and integration of single-cell transcriptomics data

Prioritization of the concepts and skills in quantitative education for graduate students in biomedical science

Actin up: shifting chromosomes toward repair, but also translocations

Transcriptional profiling of Hutchinson-Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification

Constricted migration is associated with stable 3D genome structure differences in cancer cells

sciCAN: single-cell chromatin accessibility and gene expression data integration via cycle-consistent adversarial network

Characterizing the variation in chromosome structure ensembles in the context of the nuclear microenvironment

Diagonal integration of multimodal single-cell data: potential pitfalls and paths forward

Loops, topologically associating domains, compartments, and territories are elastic and robust to dramatic nuclear volume swelling

Collaborators (7)

Greeshma Agasthya

Melike Lakadamyali

Tian Hong

Tongye Shen

Rebeca San Martin

Louis Gross

Vitaly V. Ganusov

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