Rafael de Cabo

Branch Chief

National Institutes of Health

United States

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Rafael de Cabo is a Branch Chief at the National Institutes of Health in the United States. His research focuses on the mechanisms of aging and longevity, with recent articles examining the role of mitochondrial pathways, caloric restriction, and nutritional interventions in healthspan enhancement. He has contributed to studies exploring sex-dependent responses in metabolism and the influence of microRNA on hunger signaling, among other areas of interest.

Articles (10)

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2025

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2022

Collaborators (7)

Yajaira Suárez

Professor

Yale University School of Medicine

UNITED STATES

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Tamas Horvath

Professor & Chair

Yale University School of Medicine

UNITED STATES

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Sundeep Khosla

UNITED STATES

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Hitoshi Watanabe

Columbia University

UNITED STATES

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Taiyi Kuo

Columbia University Irving Medical Center

UNITED STATES

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Domenico Accili

UNITED STATES

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Joseph Baur

Associate Professor

University of Pennsylvania

UNITED STATES

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Rafael de Cabo

Research Interests

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Articles (10)

Adaptations of mitochondrial, autophagy and nutrient sensing pathways in the liver from long-lived mice overexpressing CYB5R3 are sex-dependent and involve inter-organ responses

Promoting health and survival through lowered body temperature

microRNA-33 controls hunger signaling in hypothalamic AgRP neurons

Cytochrome b5 reductase 3 overexpression and dietary nicotinamide riboside supplementation promote distinctive mitochondrial alterations in distal convoluted tubules of mouse kidneys during aging

Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy

Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes

Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop

Calorie restriction modulates the transcription of genes related to stress response and longevity in human muscle: The CALERIE study

Obesity and lifespan, a complex tango

Science-Driven Nutritional Interventions for the Prevention and Treatment of Cancer

Collaborators (7)

Yajaira Suárez

Tamas Horvath

Sundeep Khosla

Hitoshi Watanabe

Taiyi Kuo

Domenico Accili

Joseph Baur

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