Yajaira Suárez

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Professor

Yale University School of Medicine

United States

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About

Yajaira Suárez is a Professor at the Yale School of Medicine in the United States. Her research focuses on endothelial cell metabolism, vascular function, and the role of microRNAs in various metabolic disorders and atherosclerosis. Recent articles highlight her investigations into the dynamics of lipid metabolism and their implications for conditions such as obesity and liver cancer. She is also involved in studying the interactions between macrophages and vascular inflammation.

Recent Grants

Grant: Open

Insights into the molecular mechanisms regulating vascular and immune metabolism in vascular diseases

Open Date: 2021-01-15

Close Date: 2027-12-31

Grant: Close

Defining the novel mechanisms of action of endothelial ANGPTL4 in atherosclerosis

Open Date: 2021-01-01

Close Date: 2023-12-31

Articles (19)

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2025

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2021

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2021

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2021

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2021

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2021

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2021

Collaborators (17)

Marcelo Dietrich

Professor

Yale University

UNITED STATES

Yajaira Suárez

Research Interests

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About

Recent Grants

Articles (19)

Intracellular endothelial cell metabolism in vascular function and dysfunction

Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring

Heterogeneity of hepatocyte dynamics restores liver architecture after chemical, physical or viral damage

microRNA-33 controls hunger signaling in hypothalamic AgRP neurons

miR-33 deletion in hepatocytes attenuates NAFLD-NASH-HCC progression

Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice

Macrophage-Derived 25-Hydroxycholesterol Promotes Vascular Inflammation, Atherogenesis, and Lesion Remodeling

Suppression of angiopoietin-like 4 reprograms endothelial cell metabolism and inhibits angiogenesis

Antagonism of miR-148a attenuates atherosclerosis progression in APOB<sup>TG</sup>Apobec<sup>-/-</sup>Ldlr<sup>+/-</sup> mice: A brief report.

Targeted Suppression of miRNA-33 Using pHLIP Improves Atherosclerosis Regression.

Targeted Suppression of miRNA-33 Using pHLIP Improves Atherosclerosis Regression

Deficiency of histone lysine methyltransferase SETDB2 in hematopoietic cells promotes vascular inflammation and accelerates atherosclerosis

Loss of hepatic miR-33 improves metabolic homeostasis and liver function without altering body weight or atherosclerosis

Desmosterol suppresses macrophage inflammasome activation and protects against vascular inflammation and atherosclerosis.

MMAB promotes negative feedback control of cholesterol homeostasis.

Hepatocyte-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice.

Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice.

miR-33 in cardiometabolic diseases: lessons learned from novel animal models and approaches.

Gene Expression Signature in Patients With Symptomatic Peripheral Artery Disease.

Collaborators (17)

Marcelo Dietrich

Gerald Shulman

Wendy Brown

Rafael de Cabo

Tamas Horvath

Chrysovalantou Eleni Xirouchaki

Martin Kaczocha

Leigh Goedeke

Carlos Fernández-Hernando

Iwao Ojima

Alicia Carmen Bort Bueno

Elisa Araldi

Daniel Greif

Emily Goldberg

Bal Krishna Chaube

Elina Ikonen

Timothy Osborne

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