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Rafael Rezende

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Assistant Professor of Neurology

Brigham and Women's Hospital

United States

Research Interests

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About

Dr. Rafael Rezende is an Assistant Professor of Neurology at Brigham and Women's Hospital in the United States. His research encompasses areas including immunology related to COVID-19, the interplay between the intestinal microenvironment and immune cell function, and the mechanisms of oral tolerance. His recent publications reflect his commitment to advancing the understanding of immune responses and their implications in various health contexts.

Recent Grants

Grant: Open

Modulation of Microglia and Astrocytes to Treat Alzheimer's Disease and Related Dementias

Open Date: 2024-04-15

Close Date: 2027-04-14

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Collaborators (6)

Bruce Levy

Dean and Executive Vice-Chancellor for Medical Affairs

University of Washington Medical Center

UNITED STATES

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Davide Mangani

Senior Scientist

Institute for Research in Biomedicine

SWITZERLAND

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Raja-Elie E. Abdulnour

Editor-in-Chief, NEJM Journal Watch

UMass Medical School

UNITED STATES

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Xiaoli Liu

Assistant Professor

Brigham and Women's Hospital

UNITED STATES

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Bruna Araujo David

Assistant Professor

Queen's University

CANADA

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Charles N. Serhan

Professor and Center Director

Brigham and Women's Hospital and Harvard Medical School

UNITED STATES

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Rafael Rezende

Research Interests

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About

Recent Grants

Articles (19)

15-Lipoxygenase expressing neutrophils promote Acute Lung Injury resolution

Breast milk-derived signals regulate epithelial cells maturation and γδ-IEL colonization to shape early life intestinal homeostasis

Dimethyl fumarate protects from experimental autoimmune encephalomyelitis by modulating colonic immune cells

Dissecting Zika Virus pathogenesis through maternal-fetal immune interactions and sex-based susceptibility

Gamma-Delta T cell-microglia crosstalk drives CD8<SUP>+</SUP> T cell infiltration and promotes Alzheimer's-like pathology in APP/PS1 mice

High-fat diet causes rapid loss of intestinal group 3 innate lymphoid cells through microbiota-driven inflammation and mitochondrial stress

Influence of the absence of TRPM5 in CD4 T cells during the inflammatory response in autoimmune colitis induced by adoptive cell transfer

Postnatal liver B cell precursors contribute to the establishment of a mature B cell pool in secondary lymphoid organs in mice

Systems-level transcriptomic analysis reveals synapse-related gene dysregulation in peripheral leukocytes of MDD patients

Gamma-delta T cell-microglia crosstalk promotes CD8 T cells infiltration into the brain and contributes to AD pathogenesis in APP/PS1 model

Integrative neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder

Japanese quail production in Brazil: historic, challenges and opportunities

Modulation of neuroimmune cytokine networks by antidepressants: implications in mood regulation

Nasal anti-CD3 monoclonal antibody ameliorates traumatic brain injury, enhances microglial phagocytosis and reduces neuroinflammation via IL-10-dependent T<sub>reg</sub>-microglia crosstalk

Physiological accumulation of lipid droplets in the newborn liver during breastfeeding is driven by TLR4 ligands

Siglec-F<SUP>+</SUP> neutrophils promote the resolution of acute lung injury through ALOX15 induction

Nasal administration of anti-CD3 mAb (Foralumab) downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells in subjects with COVID-19

The intestinal microenvironment shapes macrophage and dendritic cell identity and function

Oral tolerance: an updated review

Collaborators (6)

Bruce Levy

Davide Mangani

Raja-Elie E. Abdulnour

Xiaoli Liu

Bruna Araujo David

Charles N. Serhan

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