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Raffaella Santoro

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Professor

University of Zurich

Switzerland

Research Interests

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Professors in Switzerland Professors in Cell Biology Cell Biology professors in Switzerland

Recent Grants

Grant: Close

Integrative genomic and proteomic analyses to dissect nucleolus functions in aggressive prostate cancer

Open Date: 2023-01-01

Close Date: 2025-12-01

Grant: Close

Molecular and functional analysis of the nucleolus in 3D genome organization during early embryo development

Open Date: 2022-08-01

Close Date: 2025-07-01

Grant: Close

Analysis of the nucleolus and nucleolar chromatin factors in the regulation of genome architecture and function of stem cells

Open Date: 2021-09-01

Close Date: 2024-08-01

Grant: Close

Analysis of the nucleolus in genome organization and function

Open Date: 2018-09-01

Close Date: 2024-08-01

Articles (19)

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Collaborators (21)

Jean-Philippe Theurillat

Associate Professor

Università del Salento

SWITZERLAND

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Constance Ciaudo Beyer

Head of Business Development

FRANCE

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Richard Patryk Ngondo

Maître de conférences / Associate professor

University of Strasbourg

FRANCE

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Helena Fulka

Institute of Experimental Medicine ASCR

CZECH REPUBLIC

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Hanna K. A. Mikkola

Professor

University of California, Los Angeles

UNITED STATES

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Alessandro Mengozzi

Assistant Professor

University of Pisa

ITALY

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Célia Baroux

Lecturer & Group Leader / PhD.Habil

University of Zurich

SWITZERLAND

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Ivo Zemp

Senior Scientist

ETH Zürich

SWITZERLAND

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Vikram Panse

SWITZERLAND

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Beat Bornhauser

University Children's Hospital Zurich

SWITZERLAND

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Andrea Cavalli

Group Leader

Institute for Research in Biomedicine

SWITZERLAND

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Daniel Schubert

Freie Universität Berlin

GERMANY

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Christophe TATOUT

PROF UNIV

Université Clermont Auvergne

FRANCE

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Pasqualino Loi

professore ordinario

University of Teramo

ITALY

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Ivona Kubalová

Palacký University, Olomouc

CZECH REPUBLIC

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Michael O. Hottiger

Head of Department

University of Zurich

SWITZERLAND

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Ales Pecinka

Lecturer

Palacký University, Olomouc

CZECH REPUBLIC

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Paolo Cinelli

Head of Research

University Hospital of Zurich

SWITZERLAND

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Arianna Baggiolini

Group Leader and Assistant Professor at the Università della Svizzera italiana (USI)

Institute of Cancer Research

SWITZERLAND

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Sarah Costantino

Phd, Group leader

University Hospital of Zurich

SWITZERLAND

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Juan M Vaquerizas

Chair in Developmental and Regulatory Genomics

Imperial College London

UNITED KINGDOM

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Raffaella Santoro

Research Interests

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Recent Grants

Articles (19)

Oocyte Age‐Dependent DNA Damage Can Be Reverted by the DNA Repair Competent Karyoplasm of Young Oocytes

LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis

TCF3::HLF orchestrates an enhancer-promoter network with activation of MEF2C to promote immature HSC gene expression in leukemia

Chromatin Rewiring by SETD2 Drives Lipotoxic Injury in Cardiometabolic HFpEF

Targeting FOXA1 and FOXA2 disrupts the lineage-specific oncogenic output program in prostate cancer

Single-cell dynamics of genome-nucleolus interactions captured by nucleolar laser microdissection (NoLMseq)

The nucleolar granular component mediates genome-nucleolus interactions and establishes their repressive chromatin states

PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency

An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains

BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer.

Methods for mapping 3D-chromosome architecture around nucleoli.

Argonaute proteins regulate a specific network of genes through KLF4 in mouse embryonic stem cells

Image analysis workflows to reveal the spatial organization of cell nuclei and chromosomes.

Genome-wide maps of nucleolus interactions reveal distinct layers of repressive chromatin domains.

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Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4.

BAZ2A-mediated repression via H3K14ac-marked enhancers promotes prostate cancer stem cells.

BAZ2A safeguards genome architecture of ground-state pluripotent stem cells.

Regulation and Roles of the Nucleolus in Embryonic Stem Cells: From Ribosome Biogenesis to Genome Organization.

Collaborators (21)

Jean-Philippe Theurillat

Constance Ciaudo Beyer

Richard Patryk Ngondo

Helena Fulka

Hanna K. A. Mikkola

Alessandro Mengozzi

Célia Baroux

Ivo Zemp

Vikram Panse

Beat Bornhauser

Andrea Cavalli

Daniel Schubert

Christophe TATOUT

Pasqualino Loi

Ivona Kubalová

Michael O. Hottiger

Ales Pecinka

Paolo Cinelli

Arianna Baggiolini

Sarah Costantino

Juan M Vaquerizas

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