Ralf Brandes

Director / Professor / PI

Goethe University Frankfurt

Germany

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Ralf Brandes is a Director and Professor at Goethe University Frankfurt in Germany. His research focuses on vascular biology and molecular interactions, particularly in the context of endothelial stress responses, RNA-DNA interactions, and their implications for vascular health. Recent publications include studies on the role of orphan receptor GPR153 and the impact of RNA modifications on cardiac remodeling and vascular dysfunction.

Articles (18)

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2025

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2022

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2022

Collaborators (12)

Ivan Gesteira Costa Filho

Prof.

GERMANY

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Tobias Schmid

Goethe University Frankfurt

GERMANY

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James Alexander Oo

Goethe Universität Frankfurt

GERMANY

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Matthias S. Leisegang

Goethe University Frankfurt

GERMANY

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Katrin Schröder

Goethe University Frankfurt

GERMANY

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Rabea Hinkel

Prof. Dr., head

GERMANY

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Jaya Krishnan

Professor of Molecular Cardiology

Klinikum der Johann Wolfgang Goethe-Universität Frankfurt

GERMANY

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Andrew H Baker

University of Edinburgh

UNITED KINGDOM

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Robert Fürst

Professor of Pharmaceutical Biology

Goethe University Frankfurt

GERMANY

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Jan Wenzel

University of Lübeck

GERMANY

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Ralf Gilsbach

Professor

Heidelberg University

GERMANY

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Leo Kurian

W1 Professor

GERMANY

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Ralf Brandes

Research Interests

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About

Articles (18)

Prolonged In Vivo Chemogenetic Generation of Hydrogen Peroxide by Endothelial Cells Induces Cardiac Remodelling and Vascular Dysfunction

Acetylation alchemy: how Nat10 shapes vascular health

The relevance of RNA–DNA interactions as regulators of physiological functions

Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation

LncRNAs Are Key Regulators of Transcription Factor-Mediated Endothelial Stress Responses

RNA-DNA triplexes: molecular mechanisms and functional relevance

Biophysical Investigation of RNA ⋅ DNA : DNA Triple Helix and RNA : DNA Heteroduplex Formation by the lncRNAs MEG3 and Fendrr

The endothelial-enriched lncRNA LINC00607 mediates angiogenic function

Computational Methods to Study DNA:DNA:RNA Triplex Formation by lncRNAs

RNA Modification That Breaks the Heart: RNA Acetylase Nat10 Promotes Fibrosis

Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2.

HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex.

A universal model of RNA.DNA:DNA triplex formation accurately predicts genome-wide RNA-DNA interactions.

Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling.

Calcium-Controlled Reactive Oxygen Species Afterburner Perpetuates Endothelial Damage After Radiation Therapy

Human 5-lipoxygenase regulates transcription by association to euchromatin.

Nox4 promotes endothelial differentiation through chromatin remodeling.

Acceptability and utility of a virtual pediatric transplant peer mentoring program: A mixed-methods analysis of a novel quality improvement program.

Collaborators (12)

Ivan Gesteira Costa Filho

Tobias Schmid

James Alexander Oo

Matthias S. Leisegang

Katrin Schröder

Rabea Hinkel

Jaya Krishnan

Andrew H Baker

Robert Fürst

Jan Wenzel

Ralf Gilsbach

Leo Kurian

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