Ralf-Dieter Hilgers

RWTH Aachen University

Germany

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Articles (13)

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2025

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2025

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2021

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2020

Collaborators (5)

Andrew Hooker

Professor of Pharmacometrics

Uppsala University

SWEDEN

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france Mentré

INSERM

FRANCE

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Yevgen Ryeznik

Senior Lecturer/Associate Professor

Uppsala University

SWEDEN

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Mathieu Kuchenbuch

Université de Lorraine

FRANCE

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Ruth Knight

University of Oxford

UNITED KINGDOM

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Ralf-Dieter Hilgers

Research Interests

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Articles (13)

A Pharmacometrics‐Informed Trial Simulation Framework for Optimizing Study Designs for Disease‐Modifying Treatments in Rare Neurological Disorders

Randomization in clinical trials with small sample sizes using group sequential designs

Innovative methodologies for rare diseases clinical trials

Istore: a project on innovative statistical methodologies to improve rare diseases clinical trials in limited populations

Methodological insights from the EPISTOP trial to designing clinical trials in rare diseases—A secondary analysis of a randomized clinical trial

Multi-stakeholder sessions on major innovation topics in rare disease clinical trials

Evaluation of the Fill-it-up-design to use historical control data in randomized clinical trials with two arm parallel group design

Which Randomization Methods Are Used Most Frequently in Clinical Trials? Results of a Survey by the Randomization Working Group

Confidence interval comparison: Precision of maximum likelihood estimates in LLOQ affected data

No difference in outcomes between large- and small-pore meshes in a prospective, randomized, multicenter trial investigating open retromuscular meshplasty for incisional hernia repair

Multimodal Treatment of Nasopharyngeal Carcinoma in Children, Adolescents and Young Adults-Extended Follow-Up of the NPC-2003-GPOH Study Cohort and Patients of the Interim Cohort

A roadmap to using randomization in clinical trials

Design and analysis of stratified clinical trials in the presence of bias

Collaborators (5)

Andrew Hooker

france Mentré

Yevgen Ryeznik

Mathieu Kuchenbuch

Ruth Knight

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