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Andrew Hooker

Professor of Pharmacometrics

Uppsala University

Sweden

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Research Interests

Pharmacology

90%

Pharmacotherapy

60%

Pharmacometrics

60%

Pharmacoeconomics

30%

Bioavailability

30%

Drug-drug Interaction

30%

Urinary Tract

30%

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Articles19

A Comparison of Statistical Methods for Time‐To‐Event Analyses in Randomized Controlled Trials Under Non‐Proportional Hazards

Article Link

Year:

2025

A Pharmacometrics‐Informed Trial Simulation Framework for Optimizing Study Designs for Disease‐Modifying Treatments in Rare Neurological Disorders

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Year:

2025

Item performance of the scale for the assessment and rating of ataxia in rare and ultra‐rare genetic ataxias

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Year:

2024

Optimizing the design of a pharmacokinetic trial to evaluate the dosing scheme of a novel tuberculosis drug in children living with or without HIV

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Year:

2024

Evaluation of model‐integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

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Year:

2024

Development and comparison of model‐integrated evidence approaches for bioequivalence studies with pharmacokinetic end points

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Year:

2024

Methods for non-proportional hazards in clinical trials: A systematic review

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Year:

2024

Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory

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Year:

2024

Optimizing designs in clinical trials with an application in treatment of Epidermolysis bullosa simplex, a rare genetic skin disease

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Year:

2024

Generation and application of avatars in pharmacometric modelling

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Year:

2023

How to analyze continuous and discrete repeated measures in small‐sample cross‐over trials?

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Year:

2023

Establishing the suitability of model‐integrated evidence to demonstrate bioequivalence for long‐acting injectable and implantable drug products: Summary of workshop

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Year:

2023

Tutorial for $DESIGN in NONMEM: Clinical trial evaluation and optimization

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Year:

2021

Metaheuristics for pharmacometrics

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Year:

2021

Pharmacometrics meets statistics—A synergy for modern drug development

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Year:

2021

Bounded Integer Modeling of Symptom Scales Specific to Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

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Year:

2021

Model-Informed Drug Development for Long-Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium

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Year:

2021

Integrated Item Response Theory Modeling of Multiple Patient-Reported Outcomes Assessing Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia

Article Link

Year:

2020

Item Response Theory Modeling of the International Prostate Symptom Score in Patients with Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia

Article Link

Year:

2020

Collaborators15

Johan Verbeeck

Hasselt University

BELGIUM

france Mentré

INSERM

FRANCE

Mats Karlsson

Professor

Uppsala University

SWEDEN

Konstantin Emil Thiel

Paracelsus Medical University

AUSTRIA

Yevgen Ryeznik

Senior Lecturer/Associate Professor

Uppsala University

SWEDEN

Parmesh Gajjar

Chief Technology Officer

Infex Therapeutics

UNITED KINGDOM

Weng Kee Wong

Professor

UCLA

UNITED STATES

Ralf-Dieter Hilgers

RWTH Aachen University

GERMANY

Matthis Synofzik

Professor

Hertie Institute for clinical brain research

GERMANY

Martin Posch

AUSTRIA

James E. Polli

UNITED STATES

Tobias Fellinger

Österreichische Agentur für Gesundheit und Ernährungssicherheit Geschäftsfeld Medizinmarktaufsicht

AUSTRIA

Jogarao Gobburu

Professor

University of Maryland

UNITED STATES

Elin Svensson

Professor

Uppsala University

SWEDEN

Trine Meldgaard Lund

Københavns Universitet

DENMARK

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