Ralph A Nixon

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Professor

New York University

United States

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Recent Grants

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Endosome Dysfunction in Alzheimer's Disease

Open Date: 2018-09-30

Close Date: 2023-05-31

Grant: Close

Cell and Molecular Pathobiology of Alzheimer's Disease

Open Date: 2000-02-15

Close Date: 2023-03-31

Articles (10)

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

Year:

2022

Collaborators (2)

Ju-hyun Lee

Assistnat Professor

NYU Langone Medical Center

UNITED STATES

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Eunju Im

Nathan Kline Institute for Psychiatric Research

UNITED STATES

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Ralph A Nixon

Research Interests

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Recent Grants

Articles (10)

Autophagy–lysosomal-associated neuronal death in neurodegenerative disease

Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases

A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway

Autophagy is a novel pathway for neurofilament protein degradation <i>in vivo</i>

Drug development targeting degeneration of the basal forebrain cholinergic system: its time has come

Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr<SUP>682</SUP>-phosphorylated APP βCTF

Posttranscriptional regulation of neurofilament proteins and tau in health and disease

Autolysosomal acidification failure as a primary driver of Alzheimer disease pathogenesis

Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca 2+ efflux and disrupted by PSEN1 loss of function

Collaborators (2)

Ju-hyun Lee

Eunju Im

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