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Rana Al-Sadi

Penn State College of Medicine

United States

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Research Interests

Microbiology

50%

Immunology

10%

Mucosal Biology

70%

Digestive Physiology

30%

Inflammatory Biology

30%

Host-microbiota Interaction

20%

Epithelial Biology

20%

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Recent Grants

Grant: Close

MMP-9 Modulates Intestinal Epithelial Tight Junction Barrier and Intestinal Inflammation

Open Date: 2015-07-01

Close Date: 2019-02-28

Articles13

The complete genome sequence of probiotic <i>Lactobacillus acidophilus</i> ATCC 9224 isolated from sour milk

Article Link

Year:

2024

Bifidobacterium bifidum Strain BB1 Inhibits Tumor Necrosis Factor-α–Induced Increase in Intestinal Epithelial Tight Junction Permeability via Toll-Like Receptor-2/Toll-Like Receptor-6 Receptor Complex–Dependent Stimulation of Peroxisome Proliferator-Activated Receptor γ and Suppression of NF-κB p65

Article Link

Year:

2024

Lactobacillus acidophilus inhibits the TNF-α-induced increase in intestinal epithelial tight junction permeability via a TLR-2 and PI3K-dependent inhibition of NF-κB activation

Article Link

Year:

2024

Editorial: Intestinal epithelial barrier disruption by enteric pathogens

Article Link

Year:

2023

Role of Bifidobacterium in Modulating the Intestinal Epithelial Tight Junction Barrier: Current Knowledge and Perspectives

Article Link

Year:

2023

Editorial: Role of matrix metalloproteinases and other inflammatory mediators in the disruption of the intestinal tight junction barrier

Article Link

Year:

2023

Lactobacillus acidophilus Induces a Strain-specific and Toll-Like Receptor 2–Dependent Enhancement of Intestinal Epithelial Tight Junction Barrier and Protection Against Intestinal Inflammation

Article Link

Year:

2021

<i>Bifidobacterium bifidum</i> Enhances the Intestinal Epithelial Tight Junction Barrier and Protects against Intestinal Inflammation by Targeting the Toll-like Receptor-2 Pathway in an NF-κB-Independent Manner.

Article Link

Year:

2021

Penicillin Allergy Label Increases Risk of Worse Clinical Outcomes in COVID-19.

Article Link

Year:

2021

Matrix Metalloproteinase-9 (MMP-9) induced disruption of intestinal epithelial tight junction barrier is mediated by NF-κB activation

Article Link

Year:

2021

IL-1β and the Intestinal Epithelial Tight Junction Barrier

Article Link

Year:

2021

IL1B Increases Intestinal Tight Junction Permeability by Up-regulation of MIR200C-3p, Which Degrades Occludin mRNA

Article Link

Year:

2020

Talk about micromanaging! Role of microRNAs in intestinal barrier function

Article Link

Year:

2020

Collaborators4

Manmeet Rawat

Assistant Professor

Penn State College of Medicine

UNITED STATES

Prashant Nighot

Penn State College of Medicine

UNITED STATES

Thomas Y. Ma

Penn State College of Medicine

UNITED STATES

Arun Bhunia

Professor of Food Microbiology

Purdue University

UNITED STATES

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