Raquel López Arribas

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Profesora Ayudante Doctor

Universidad Rey Juan Carlos

Spain

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About

Raquel López Arribas is an Assistant Professor at Universidad Rey Juan Carlos in Spain. Her research primarily focuses on neuroprotection, exploring pathways related to phosphorylation, drug design for Alzheimer's disease, and the synthesis of compounds with neuroprotective activity. Recent publications highlight her studies on the role of protein phosphatase 2A in neurodegenerative diseases and the development of ligands targeting multiple pathways for Alzheimer's treatment.

Recent Grants

Grant: Close

Potencial terapéutico del mantenimiento de la actividad de la proteína fosfatasa 2A: Una alternativa farmacológica para el tratamiento de las enfermedades neurodegenerativas y el cáncer

Open Date: 2020-01-01

Close Date: 2022-12-31

Grant: Close

El intercambiador sodio/calcio mitocondrial como diana terapéutica para el desarrollo de fármacos innovadores para el tratamiento de enfermedades neurodegenerativas e ictus

Open Date: 2017-01-01

Close Date: 2019-12-31

Grant: Close

La proteina fosfatasa 2A como diana terapéutica para el desarrollo de nuevos fármacos para el tratamiento de enfermedades neurodegenerativas

Open Date: 2014-01-01

Close Date: 2017-08-30

Articles (10)

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2023

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2023

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2023

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2021

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2021

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2021

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2021

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2021

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2021

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2020

Collaborators (4)

Veerle Janssens

Professor

KU Leuven

BELGIUM

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Alejandro Romero

Profesor Titular de Universidad

Universidad Complutense de Madrid Facultad de Veterinaria

SPAIN

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Cristobal de los Rios

Profesor Contratado Doctor (Lecturer)

Universidad Rey Juan Carlos - Campus de Fuenlabrada

SPAIN

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Aurélie Baguet

Université de Franche-Comté

FRANCE

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Raquel López Arribas

Research Interests

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About

Recent Grants

Articles (10)

C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer's disease targeting tauopathies.

Differential tyrosine and serine/threonine phosphorylation/dephosphorylation pathways regulate the expression of α7 versus α3β4 nicotinic receptor subtypes in mouse hippocampal neurons.

C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer?s disease targeting tauopathies

(±)-<b>BIGI-3h</b>: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease.

In Silico Prediction of the Toxic Potential of Neuroprotective Bifunctional Molecules Based on Chiral N-Propargyl-1,2-amino Alcohol Derivatives

(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease

In Silico Prediction of the Toxic Potential of Neuroprotective Bifunctional Molecules Based on Chiral <i>N</i>-Propargyl-1,2-amino Alcohol Derivatives

Synthesis and Biological Assessment of 4,1-Benzothiazepines with Neuroprotective Activity on the Ca<SUP>2+</SUP> Overload for the Treatment of Neurodegenerative Diseases and Stroke

Synthesis and Biological Assessment of 4,1-Benzothiazepines with Neuroprotective Activity on the Ca2+ Overload for the Treatment of Neurodegenerative Diseases and Stroke.

An okadaic acid fragment analogue prevents nicotine -induced resistance to cisplatin by recovering PP2A activity in non -small cell lung cancer cells

Collaborators (4)

Veerle Janssens

Alejandro Romero

Cristobal de los Rios

Aurélie Baguet

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