Veerle Janssens

Professor

KU Leuven

Belgium

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About

Veerle Janssens is a Professor at KU Leuven in Belgium. Her research focuses on genetic disorders, particularly related to phosphatases and their implications in neurodevelopmental conditions and cancer. Recent publications include studies on Houge-Janssens syndrome and the role of various PPP2R genes in disease mechanisms. Janssens's work contributes to understanding radiotherapy resistance and potential therapeutic opportunities in cancer treatment.

Articles (18)

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2025

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2025

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2021

Collaborators (11)

Wenqing Xu

Affiliate Professor

University of Washington

UNITED STATES

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Kimberly Foss

Assistant Professor

University of North Carolina

UNITED STATES

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Anna Ruiz

Institute of Research and Innovation Parc Tauli

SPAIN

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William Dobyns

Professor

University of Minnesota

UNITED STATES

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Francisco Javier Cubero

SPAIN

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Sofia Douzgou

Honorary Senior Lecturer

UNITED KINGDOM

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Cristobal de los Rios

Profesor Contratado Doctor (Lecturer)

Universidad Rey Juan Carlos - Campus de Fuenlabrada

SPAIN

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Wendy Chung

Kennedy Family Professor

Columbia University Vagelos College of Physicians and Surgeons

UNITED STATES

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Raquel López Arribas

Profesora Ayudante Doctor

Universidad Rey Juan Carlos

SPAIN

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Vesa Hytönen

University of Tampere

FINLAND

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Maja Köhn

Full Professor

University of Freiburg

GERMANY

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Veerle Janssens

Research Interests

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About

Articles (18)

Pathogenic de novo variants in PPP2R5C cause a neurodevelopmental disorder within the Houge-Janssens syndrome spectrum

Houge-Janssens syndrome

The phosphatase activity of the PPP2R5D-PP2A holoenzyme modulates liprin-α1 liquid-liquid phase separation

PPP2R5E: New gene potentially involved in specific learning disorders and myopathy.

PP2A phosphatase regulatory subunit PPP2R3C is a new positive regulator of the hedgehog signaling pathway.

The PPP2R1A cancer hotspot mutant p.R183W increases clofarabine resistance in uterine serous carcinoma cells by a gain-of-function mechanism

TIPRL1 and its ATM-dependent phosphorylation promote radiotherapy resistance in head and neck cancer

Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A

Clinical, neuroimaging and molecular characteristics ofPPP2R5D-related neurodevelopmental disorders: an expanded series with functional characterisation and genotype–phenotype analysis

A Novel Mouse Model of Combined Hepatocellular-Cholangiocarcinoma Induced by Diethylnitrosamine and Loss of Ppp2r5d

Editorial: Deciphering the etiology of rare genetic disorders associated with protein phosphatases.

PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling

Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality.

C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer's disease targeting tauopathies.

2D-DIGE Analysis of Liver Disease in Mice.

PME-1-regulated neural cell death: new therapeutic opportunities?

Clinical and molecular characteristics of a novel rare de novo variant in PPP2CA in a patient with a developmental disorder, autism, and epilepsy

Increased LGR6 Expression Sustains Long-Term Wnt Activation and Acquisition of Senescence in Epithelial Progenitors in Chronic Lung Diseases

Collaborators (11)

Wenqing Xu

Kimberly Foss

Anna Ruiz

William Dobyns

Francisco Javier Cubero

Sofia Douzgou

Cristobal de los Rios

Wendy Chung

Raquel López Arribas

Vesa Hytönen

Maja Köhn

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