Raymundo Nuñez

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Medical College of Wisconsin

United States

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Epigenetic regulation in activated macrophages through TRIM33 binding to metabolically-derived histone lactylation

Open Date: 2022-01-01

Close Date: 2023-12-31

Articles (7)

Year:

2025

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2025

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2024

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2024

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2024

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2023

Year:

2022

Collaborators (2)

Brian Smith

Associate Professor

Medical College of Wisconsin

UNITED STATES

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Daniel Sprague

Assistant Professor

Medical University of South Carolina

UNITED STATES

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Raymundo Nuñez

Research Interests

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Contact this professor

Recent Grants

Articles (7)

Polybromo-1 Bromodomain Inhibitor Selectivity Is Mediated by a Unique Ligand-Binding Pocket

Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains

Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types

The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation

Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression

Fragment-based screening by protein-detected NMR spectroscopy.

Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening

Collaborators (2)

Brian Smith

Daniel Sprague

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