Rintaro Hara

Project Junior Associate Professor

Tokyo Medical and Dental University

Japan

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About

Dr. Rintaro Hara is a Project Junior Associate Professor at Tokyo Medical and Dental University in Japan. His research focuses on therapeutic approaches for Duchenne Muscular Dystrophy, molecular dynamics simulations of RNA interactions, and the synthesis of novel oligonucleotide structures. His recent publications include studies on splice switching technologies and the neurotoxicity of antisense oligonucleotides.

Articles (17)

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2025

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2021

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2021

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2021

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2020

Collaborators (3)

Tetsuya Nagata

Tokyo Medical and Dental University

JAPAN

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Kotaro Yoshioka

Project Assistant Professor

Tokyo Medical and Dental University

JAPAN

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Fumika Sakaue

Research Assistant Professor

Tokyo Medical and Dental University

JAPAN

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Rintaro Hara

Research Interests

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About

Articles (17)

G-Quadruplex-Based Splice Switching as a Therapeutic Approach in Duchenne Muscular Dystrophy

Comparison of interaction between antimiR and microRNA versus HDO-antimiR and microRNA by molecular dynamics simulation

Development of cationic oligodiaminogalactoses specifically binding to duplex RNA, but not to duplex DNA

Favorable efficacy and reduced acute neurotoxicity by antisense oligonucleotides with 2',4'-BNA/LNA with 9-(aminoethoxy)phenoxazine

Favorable efficacy and reduced acute neurotoxicity by antisense oligonucleotides with 2',4'-BNA/LNA with 9-(aminoethoxy)phenoxazine (Mar, 10.1016/j.omtn.2024.102161, 2024)

Heteroduplex oligonucleotide technology boosts oligonucleotide splice switching activity of morpholino oligomers in a Duchenne muscular dystrophy mouse model

Synthesis of P-Modified DNA from Boranophosphate DNA as a Precursor via Acyl Phosphite Intermediates

Solid-Phase Synthesis of Glycosyl Phosphate Repeating Units via Glycosyl Boranophosphates as Stable Intermediates

TDP‐43 N‐terminal domain dimerisation or spatial separation by RNA binding decreases its propensity to aggregate

Properties of artificial cationic oligodiaminosaccharides and oligopeptides that bind to A-type oligonucleotide duplexes

Solid-Phase Synthesis of Glycosyl Phosphate Repeating Units via Glycosyl Boranophosphates as Stable Intermediates

Synthesis of P-Modified DNA from Boranophosphate DNA as a Precursor via Acyl Phosphite Intermediates

Synthesis and properties of oligodiaminogalactoses that bind to A-type oligonucleotide duplexes

Solid-Phase Stereocontrolled Synthesis of Oligomeric P-Modified Glycosyl Phosphate Derivatives Using the Oxazaphospholidine Method

Inhibition of off-target cleavage by RNase H using an artificial cationic oligosaccharide

Solution-phase synthesis of oligodeoxyribonucleotides using the H-phosphonate method with N-unprotected 5′-phosphite monomers

Synthesis and properties of DNA oligomers containing stereopure phosphorothioate linkages and C-5 modified deoxyuridine derivatives

Collaborators (3)

Tetsuya Nagata

Kotaro Yoshioka

Fumika Sakaue

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