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Rob Wolthuis

Associate Professor

Amsterdam UMC

Netherlands

Research Interests

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Professors in Netherlands Professors in Cell Biology Cell Biology professors in Netherlands

About

Rob Wolthuis is an Associate Professor at Amsterdam UMC in the Netherlands. His research primarily focuses on CRISPR technology, gene mutations related to cancer and developmental disorders, and DNA repair mechanisms. He has authored several recent articles exploring topics such as non-invasive prenatal testing, advanced genomic diagnostics, and therapeutic strategies for cancer treatment.

Articles (11)

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2025

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (5)

Raquel A. Oliveira

Associate Professor

Universidade Católica Portuguesa

PORTUGAL

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Job de Lange

VU medisch centrum

NETHERLANDS

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Jeanne Elisabeth van Dongen

Catharina Ziekenhuis

NETHERLANDS

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Erik A. Sistermans

NETHERLANDS

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Michael R Speicher

Medical University of Graz

AUSTRIA

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Rob Wolthuis

Research Interests

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Articles (11)

Recent advances in CRISPR-based single-nucleotide fidelity diagnostics

BIRC2–BIRC3 amplification: a potentially druggable feature of a subset of head and neck cancers in patients with Fanconi anemia

Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregation

Fragmentomic cfDNA Patterns in Noninvasive Prenatal Testing and Beyond

ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation

ERCC1 mutations impede DNA damage repair and cause liver and kidney dysfunction in patients

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells

Point-of-care CRISPR/Cas nucleic acid detection: Recent advances, challenges and opportunities

Chemopreventive targeted treatment of head and neck precancer by Wee1 inhibition

Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2

WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion

Collaborators (5)

Raquel A. Oliveira

Job de Lange

Jeanne Elisabeth van Dongen

Erik A. Sistermans

Michael R Speicher

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