Robert P Coppes

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Full Professor

Universitair Medisch Centrum Utrecht

Netherlands

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Recent Grants

Grant: Close

Treatment of radiation-induced hyposalivation using cell therapy (STOPXERO)

Open Date: 2020-10-01

Close Date: 2024-09-01

Grant: Close

Preclinical testing of prophylactic treatments for radiotherapy-induced cardiopulmonary complications

Open Date: 2019-01-01

Close Date: 2023-01-01

Grant: Close

Increasing therapeutic window of proton therapy in brain, head and neck cancer (INTO-PROT)

Open Date: 2018-09-01

Close Date: 2023-09-01

Grant: Close

IMage guided Proton/pArticle infrastructure for pre-Clinical sTudies (IMPACT)

Open Date: 2018-01-01

Close Date: 2023-01-01

Grant: Close

Hemodynamic changes in the cardiopulmonary circulation after thoracic radiotherapy

Open Date: 2018-01-01

Close Date: 2023-01-01

Articles (20)

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Collaborators (14)

Cornelia Brunner

Ulm University Medical Center

GERMANY

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Hidde Haisma

Head Dept. of Therapeutic Gene Modulation

University of Groningen

NETHERLANDS

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Abel Soto-Gamez

University of Edinburgh

UNITED KINGDOM

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Karl T. Butterworth

UNITED KINGDOM

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Kirsten Lauber

Head of Molecular Radiation Oncology

LMU Klinikum

GERMANY

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John Plukker

prof. MD.PhD

University Medical Center Groningen

NETHERLANDS

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Sarah Pringle

Assistant Professor

University Medical Center Groningen

NETHERLANDS

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Bahez Gareb

Universitair Medisch Centrum Groningen (UMCG)

NETHERLANDS

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Patricia Boya

Full Professor

University of Fribourg

SWITZERLAND

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Rudolf Fehrmann

Tenure track associate professor

University Medical Center Groningen

NETHERLANDS

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Nils Cordes

Technische Universität Dresden

GERMANY

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Wouter Zandee

NETHERLANDS

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Amalia Dolga

Associate Professor

University of Groningen

NETHERLANDS

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Gerald de Haan

University Medical Center Groningen

NETHERLANDS

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Robert P Coppes

Research Interests

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Recent Grants

Articles (20)

Sparing of the heart facilitates recovery from cardiopulmonary side effects after thoracic irradiation

MET-receptor targeted fluorescent imaging and spectroscopy to detect multifocal papillary thyroid cancer

Small Molecule MIF Modulation Enhances Ferroptosis by Impairing DNA Repair Mechanisms

Organoid-based personalized medicine: from tumor outcome prediction to autologous transplantation

Radiation-induced DNA double-strand breaks in cortisol exposed fibroblasts as quantified with the novel foci-integrated damage complexity score (FIDCS)

Radiation-induced xerostomia is related to stem cell dose-dependent reduction of saliva production

Proton therapy induces a local microglial neuroimmune response

Optimization of the Production Process of Clinical-Grade Human Salivary Gland Organoid-Derived Cell Therapy for the Treatment of Radiation-Induced Xerostomia in Head and Neck Cancer

Resistance of HNSCC cell models to pan-FGFR inhibition depends on the EMT phenotype associating with clinical outcome

Mitophagy induction improves salivary gland stem/progenitor cell function by reducing senescence after irradiation

Roadmap for precision preclinical x-ray radiation studies

Organoids as a model to study intestinal and liver dysfunction in severe malnutrition

Patient-derived parathyroid organoids as a tracer and drug-screening application model

Role of quiescent cells in the homeostatic maintenance of the adult submandibular salivary gland

Intraoperative MET-receptor targeted fluorescent imaging and spectroscopy for lymph node detection in papillary thyroid cancer

Radiation-induced cardiac side-effects

Role of mTOR through Autophagy in Esophageal Cancer Stemness

Thyroid Gland Organoids

Autophagy induction during stem cell activation plays a key role in salivary gland self-renewal

Parotid Gland Stem Cell Sparing Radiation Therapy for Patients With Head and Neck Cancer

Collaborators (14)

Cornelia Brunner

Hidde Haisma

Abel Soto-Gamez

Karl T. Butterworth

Kirsten Lauber

John Plukker

Sarah Pringle

Bahez Gareb

Patricia Boya

Rudolf Fehrmann

Nils Cordes

Wouter Zandee

Amalia Dolga

Gerald de Haan

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