Rowan Hardy

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Assistant Professor in Steroid Metabolism and Signalling

University of Birmingham

United Kingdom

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About

Rowan Hardy is an Assistant Professor in Steroid Metabolism and Signalling at the University of Birmingham, UK. His research focuses on steroid metabolism, kidney disease, muscle atrophy, and the therapeutic applications of corticosteroids in chronic inflammation. Recent publications include studies on the impact of glucocorticoid therapy on muscle wasting and the role of 11β-Hydroxysteroid Dehydrogenase in various physiological processes.

Recent Grants

Grant: Open

Targeting steroid metabolism to prevent muscle wasting in chronic inflammation

Open Date: 2023-08-01

Close Date: 2027-08-01

Grant: Close

De-risking pilot study for targeted delivery of oligonucleotide therapeutics using conjugated antibodies into musculoskeletal cells of the human joint

Open Date: 2022-09-01

Close Date: 2023-03-01

Grant: Close

Examining the Role of Steroid Metabolism by 11β-HSD1 in the Action of Vamorolone Picture

Open Date: 2022-04-01

Close Date: 2023-09-01

Grant: Close

Parsing the anti-inflammatory and immuno-suppressive effects of glucocorticoids

Open Date: 2021-09-01

Close Date: 2024-08-01

Grant: Close

Unlocking cortisol activation in muscle as a treatable cause of muscle wasting in kidney failure

Open Date: 2020-09-01

Close Date: 2023-07-01

Articles (11)

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2025

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2021

Year:

2021

Year:

2021

Collaborators (16)

Mette Marie Rosenkilde

Københavns Universitet

DENMARK

Rowan Hardy

Research Interests

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About

Recent Grants

Articles (11)

Impaired 11β-Hydroxysteroid Dehydrogenase Type 2 Activity in Kidney Disease Disrupts 11-Oxygenated Androgen Biosynthesis

Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders: Successes and Challenges

GIP reduces osteoclast activity and improves osteoblast survival in primary human bone cells

11β-HSD1 determines the extent of muscle atrophy in a model of acute exacerbation of COPD

Synthesis, molecular docking, bio-evaluation and quantitative structure activity relationship of new chalcone derivatives as antioxidants

Cortisol excess in chronic kidney disease - A review of changes and impact on mortality.

Bench to Bedside: Modelling Inflammatory Arthritis

11β-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation

Global Deletion of 11β-HSD1 Prevents Muscle Wasting Associated with Glucocorticoid Therapy in Polyarthritis

Assessment of Alveolar Macrophage Dysfunction Using an in vitro Model of Acute Respiratory Distress Syndrome

11βHSD1 Inhibition with AZD4017 Improves Lipid Profiles and Lean Muscle Mass in Idiopathic Intracranial Hypertension

Collaborators (16)

Mette Marie Rosenkilde

Caroline Gorvin

Amy J Naylor

Karl‐Heinz Storbeck

Brent van der Heyden

Karim Raza

Claire Martin

Alexander Rauch

Michael Sagmeister

Angela, E Taylor

Mark Cooper

Simon Jones

Andrew Filer

Marie McIlroy

Morten Frost

Ramon C. J. Langen

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