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Mette Marie Rosenkilde

Københavns Universitet

Denmark

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Research Interests

Cell Biology

30%

Biochemistry

50%

G Protein-coupled Receptor

90%

Insulin Resistance

60%

Insulin Signaling

40%

Beta Cell

40%

Islet Biology

30%

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Articles20

Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node

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Year:

2024

Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling

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2024

Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes

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2024

GIP-derived GIP receptor antagonists – a review of their role in GIP receptor pharmacology

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2024

Advancing the field of viroporins-Structure, function and pharmacology: IUPHAR Review X.

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2024

Relevance of G protein‐coupled receptor (GPCR) dynamics for receptor activation, signalling bias and allosteric modulation

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2024

Advances in incretin-based therapeutics for obesity

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2024

AT-7687, a novel GIPR peptide antagonist, combined with a GLP-1 agonist, leads to enhanced weight loss and metabolic improvements in cynomolgus monkeys

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2024

Alpha-cyclodextrin increases glucagon-like peptide-1 secretion in multiple models and improves metabolic status in mice

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2024

Effects of exogenous GIP and GLP-2 on bone turnover in individuals with type 2 diabetes

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2024

Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice

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Year:

2023

The Secretome of Parental and Bone Metastatic Breast Cancer Elicits Distinct Effects in Human Osteoclast Activity after Activation of β2 Adrenergic Signaling

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2023

GIP reduces osteoclast activity and improves osteoblast survival in primary human bone cells

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2023

Identification of a Salt Bridge That Is Functionally Important for Chemokine Receptor CXCR1 but not CXCR2

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2023

The importance of glucose‐dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

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2023

Glycine: a long-sought novel ligand for GPR158

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2023

Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation

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Year:

2023

Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system

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Year:

2023

Loss of Adgra3 causes obstructive azoospermia with high penetrance in male mice

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Year:

2023

GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection

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Year:

2022

Collaborators40

Stephen Griffin

Professor of Cancer Virology

University of Leeds

UNITED KINGDOM

Bo Hjorth Bentzen

Københavns Universitet

DENMARK

Caroline Gorvin

University of Birmingham

UNITED KINGDOM

Stefan Sattler

Københavns Universitet

DENMARK

João Lobo

Lecturer in Pathology - Master degree in Medicine

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar

PORTUGAL

Matthew J. Sweet

University of Queensland

AUSTRALIA

Søren Brunak

DENMARK

Jenna Elizabeth Hunt

Københavns Universitet

DENMARK

Karina Banasik

Københavns Universitet

DENMARK

Filip K Knop

University of Copenhagen

DENMARK

Maja Lind Nybo

Københavns Universitet

DENMARK

Anna Drzazga

Københavns Universitet

DENMARK

Katharina Ronacher

Professorial Research Fellow/Professor

AUSTRALIA

Peter Lindquist

Københavns Universitet

DENMARK

Kimmie Vestergaard Sørensen

Københavns Universitet

DENMARK

Maud Eline Ottenheijm

Københavns Universitet

DENMARK

Volker Lauschke

Assistant Professor

Karolinska Institutet

SWEDEN

Charlotte Bayer Christiansen

Københavns Universitet

DENMARK

Majken Karoline Jensen

Københavns Universitet

DENMARK

Meriem Lamghari

Instituto Universitário de Ciências da Saúde

PORTUGAL

Anniek Frederike Lubberding

Københavns Universitet

DENMARK

Sara Ludovico Garcia

Københavns Universitet

DENMARK

Alexander Rauch

Associate Professor

University of Southern Denmark

DENMARK

Charlotte Mehlin Sorensen

Københavns Universitet

DENMARK

Thomas Jespersen

Københavns Universitet

DENMARK

Jesper Skovhus Thomsen

Aarhus University

DENMARK

Jens Juul Holst

Københavns Universitet

DENMARK

Jacob Tfelt-Hansen

Københavns Universitet

DENMARK

Shane Wright

Karolinska Institutet

SWEDEN

Cheng Xiang Foo

Mater Research Institute The University of Queensland

AUSTRALIA

Bolette Hartmann

Københavns Universitet

DENMARK

Marie Winther-Sørensen

Københavns Universitet

DENMARK

Sara Tangmose Larsen

Københavns Universitet

DENMARK

Alexander Khromykh

Professor

University of Queensland

AUSTRALIA

Rowan Hardy

Assistant Professor in Steroid Metabolism and Signalling

University of Birmingham

UNITED KINGDOM

Luca Soattin

Københavns Universitet

DENMARK

Sarah Dalgas Nissen

Københavns Universitet

DENMARK

Mark Smits

Københavns Universitet

DENMARK

Lærke Smidt Gasbjerg

Københavns Universitet

DENMARK

Morten Frost

DENMARK

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