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Rupert Beale

Clinician Scientist Group Leader

The Francis Crick Institute

United Kingdom

Research Interests

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Professors in United Kingdom Professors in Epidemiology Epidemiology professors in United Kingdom

Articles (20)

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Collaborators (19)

Harriet Mears

Academic , Lecturer in Virology

University of Bristol

UNITED KINGDOM

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Jonathan Heeney

Professor of Comparative Pathology

University of Cambridge

UNITED KINGDOM

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George Kassiotis

Imperial College London

UNITED KINGDOM

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Alejandro Arenas-Pinto

University College London

UNITED KINGDOM

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Gavin Kelly

The Francis Crick Institute

UNITED KINGDOM

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Andrew Copas

University College London

UNITED KINGDOM

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Victoria Hall

Principal Research Fellow

University College London

UNITED KINGDOM

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Bryan Williams

Chair of Medicine

University College London

UNITED KINGDOM

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Graham McIlroy

NIHR Academic Clinical Lecturer in Haematology

University of Birmingham

UNITED KINGDOM

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Alex Byrne

Senior Bioinformatician

The Francis Crick Institute

UNITED KINGDOM

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David Crossman

Dean of Faculty of Medicine

University of St. Andrews

UNITED KINGDOM

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Lesley Price

Glasgow Caledonian University

UNITED KINGDOM

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Mike Devine

Clinical Science Group Leader

The Francis Crick Institute

UNITED KINGDOM

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Abigail Severn

King’s College London

UNITED KINGDOM

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Daniela De Angelis

Professor

University of Cambridge

UNITED KINGDOM

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Dan Wootton

Senior Clinical Lecturer

University of Liverpool

UNITED KINGDOM

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Kieran Woolcock

University of Glasgow

UNITED KINGDOM

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Oliver Stirrup

University College London

UNITED KINGDOM

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Katie Munro

UK Health Security Agency

UNITED KINGDOM

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Rupert Beale

Research Interests

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Articles (20)

Assessment of human immunity to A/H3N2 influenza subclade K during 2025 emergence

Cohort Profile: SARS-CoV-2 Immunity and Reinfection EvaluatioN (SIREN)

High rates of SARS-CoV-2 reinfection in residents of long term care facilities despite robust spike-specific immunity following serial vaccination.

Impact of first SARS-CoV-2 infection variant on serological responses against Omicron: Findings from the SIREN study.

Adults in Ghana generate higher and more durable neutralising antibody titres following primary course COVID-19 vaccination than matched UK adults: The HERITAGE Study.

Investigation of Influenza A(H5N1) Virus Neutralization by Quadrivalent Seasonal Vaccines, United Kingdom, 2021-2024

Real-time estimation of immunological responses against emerging SARS-CoV-2 variants in the UK: a mathematical modelling study

Immunogenicity of three-dose COVID-19 vaccines in people living with multiple sclerosis.

Caspase cleavage of influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production

Autophagy machinery as exploited by viruses.

Effect of second booster vaccinations and prior infection against SARS-CoV-2 in the UK SIREN healthcare worker cohort

Immunogenicity of third dose COVID-19 vaccine strategies in patients who are immunocompromised with suboptimal immunity following two doses (OCTAVE-DUO): an open-label, multicentre, randomised, controlled, phase 3 trial

The V-ATPase/ATG16L1 axis is controlled by the V1H subunit.

Conjugation of ATG8s to single membranes at a glance

Divergent performance of vaccines in the UK autumn 2023 COVID-19 booster campaign

COVID-19 in non-hospitalised adults caused by either SARS-CoV-2 sub-variants Omicron BA.1, BA.2, BA.4/5 or Delta associates with similar illness duration, symptom severity and viral kinetics, irrespective of vaccination history.

Combined analyses of within-host SARS-CoV-2 viral kinetics and information on past exposures to the virus in a human cohort identifies intrinsic differences of Omicron and Delta variants.

SARS-CoV-2 mucosal neutralising immunity after vaccination.

Antibody correlates of protection against Delta infection after vaccination: A nested case-control within the UK-based SIREN study.

CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study.

Collaborators (19)

Harriet Mears

Jonathan Heeney

George Kassiotis

Alejandro Arenas-Pinto

Gavin Kelly

Andrew Copas

Victoria Hall

Bryan Williams

Graham McIlroy

Alex Byrne

David Crossman

Lesley Price

Mike Devine

Abigail Severn

Daniela De Angelis

Dan Wootton

Kieran Woolcock

Oliver Stirrup

Katie Munro

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