Sammy Chan

University College London

United Kingdom

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Articles (5)

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Collaborators (4)

Christopher Waudby

University College London

UNITED KINGDOM

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Alkistis Mitropoulou

University College London

UNITED KINGDOM

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Minkoo Ahn

University of Bristol

UNITED KINGDOM

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John Christodoulou

University College London

UNITED KINGDOM

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Sammy Chan

Research Interests

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Articles (5)

The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein

Modulating co-translational protein folding by rational design and ribosome engineering

Interactions between nascent proteins and the ribosome surface inhibit co-translational folding

Nascent chains can form co-translational folding intermediates that promote post-translational folding outcomes in a disease-causing protein

Common sequence motifs of nascent chains engage the ribosome surface and trigger factor

Collaborators (4)

Christopher Waudby

Alkistis Mitropoulou

Minkoo Ahn

John Christodoulou

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