John Christodoulou

University College London

United Kingdom

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Articles (13)

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2024

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2024

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (9)

Tuomas Knowles

Professor of Physical Chemistry and Biophysics

University of Cambridge

UNITED KINGDOM

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Christopher Waudby

University College London

UNITED KINGDOM

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Nick Lane

University College London

UNITED KINGDOM

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Sean F Jordan

Associate Professor in Chemistry

Dublin City University

IRELAND

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Minkoo Ahn

University of Bristol

UNITED KINGDOM

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Anne Wentink

Assistant Professor

Leiden University

NETHERLANDS

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Sammy Chan

University College London

UNITED KINGDOM

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Rajesh Raj

Clinical Associate Professor

University of Tasmania School of Medicine

AUSTRALIA

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Nikos Pinotsis

Birkbeck University of London

UNITED KINGDOM

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John Christodoulou

Research Interests

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Articles (13)

Thermodynamic profiles for cotranslational trigger factor substrate recognition

The ribosome lowers the entropic penalty of protein folding

The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein

Any symptom, in any organ, at any age: A case report of multiple genetic diagnoses mimicking mitochondrial disease in an adult with kidney disease

An intrinsic temporal order of c-JUN N-terminal phosphorylation regulates its activity by orchestrating co-factor recruitment

Thermodynamics of co-translational folding and ribosome–nascent chain interactions

Spontaneous assembly of redox-active iron-sulfur clusters at low concentrations of cysteine.

Interactions between nascent proteins and the ribosome surface inhibit co-translational folding

Nascent chains can form co-translational folding intermediates that promote post-translational folding outcomes in a disease-causing protein

Optimal design of adaptively sampled NMR experiments for measurement of methyl group dynamics with application to a ribosome-nascent chain complex

Nascent chain dynamics and ribosome interactions within folded ribosome–nascent chain complexes observed by NMR spectroscopy

High-resolution ex vivo NMR spectroscopy of human Z α1-antitrypsin

Two-dimensional NMR lineshape analysis of single, multiple, zero and double quantum correlation experiments

Collaborators (9)

Tuomas Knowles

Christopher Waudby

Nick Lane

Sean F Jordan

Minkoo Ahn

Anne Wentink

Sammy Chan

Rajesh Raj

Nikos Pinotsis

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