Samuel Lucas
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Recent Grants
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‘Running blue’: The effects of blueberry intake on cerebrovascular and cognitive responses to exercise in low and high-fit young adults
Open Date: 2021-09-01
Close Date: 2023-08-01
Grant: Close
Effects of a non-invasive neuroprosthesis on functional capacity in individuals with spinal cord injury
Open Date: 2021-09-01
Close Date: 2025-03-01
Grant: Close
Detecting, predicting, and preventing acute mountain sickness: Optimising the utility of pulse oximetry.
Open Date: 2021-08-01
Close Date: 2022-12-01
Grant: Close
Fitness, Ageing and Bilingualism (FAB): The benefits of regular physical activity and bilingualism for language abilities in healthy ageing
Open Date: 2020-10-01
Close Date: 2023-10-01
Grant: Close
Developing a gold standard for Cerebrovascular Reactivity (CVR) measures: a metric of brain vascular health
Open Date: 2017-12-01
Close Date: 2018-11-01
Articles (17)
Aim The present systematic review and meta‐analysis aimed to compare the effect of moderate‐ versus high‐intensity aerobic exercise on cardiorespiratory fitness (CRF) in older adults, taking into account the volume of exercise completed. Methods The databases MEDLINE (Ovid), EMBASE (Ovid), and CENTRAL (Cochrane Library) were searched to identify randomized controlled trials (RCTs). Two reviewers extracted data and assessed bias. Comprehensive Meta‐Analysis software calculated overall effect size, intensity differences, and performed meta‐regression analyses using pre‐to‐post intervention or change scores of peak oxygen uptake (V̇O 2 peak). The review included 23 RCTs with 1332 older adults (intervention group: n = 932; control group: n = 400), divided into moderate‐intensity (435 older adults) and high‐intensity (476 older adults) groups. Results Meta‐regression analysis showed a moderate, but not significant, relationship between exercise intensity and improvements in V̇O 2 peak after accounting for the completed exercise volume ( β = 0.31, 95% CI = [−0.04; 0.67]). Additionally, studies comparing moderate‐ versus high‐intensity revealed a small, but not significant, effect in favor of high‐intensity (Hedges' g = 0.20, 95% CI = [−0.02; 0.41]). Finally, no significant differences in V̇O 2 peak improvements were found across exercise groups employing various methods, modalities, and intensity monitoring strategies. Conclusion Findings challenge the notion that high‐intensity exercise is inherently superior and indicate that regular aerobic exercise, irrespective of the specific approach and intensity, provides the primary benefits to CRF in older adults. Future RCTs should prioritize valid and reliable methodologies for monitoring and reporting exercise volume and adherence among older adults.
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Collaborators (24)
George Balanos
Associate Professor
University of Birmingham
Lisa Hill
University of Birmingham
Mark Thaller
University of Birmingham
James Faulkner
Reader
University of Winchester
Anne Daykin
Lecturer in Physiotherapy
University of Gloucestershire
Martin Whitham
Senior Lecturer
University of Birmingham
Olivia Grech
University of Birmingham
Rebekah Lucas
University of Birmingham
Liana Machado
University of Otago
James David Cotter
University of Otago
Blake G. Perry
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Georgios Tsermoulas
University of Birmingham
Jonathan Smirl
Assistant Professor
University of Calgary
N. Tim Cable
Manchester Metropolitan University
Simon Fryer
Senior Lecturer in Sport & Exercise
University of Gloucestershire
Karen Mullinger
University of Birmingham
Tom Nightingale
University of Birmingham
Catarina Rendeiro
Assistant Professor
University of Birmingham
Hannah Lyons
Clinical Headache Fellow
University Hospitals Birmingham NHS Foundation Trust
David MacLeod
Associate Clinical Professor
Duke University
Alexandra J. Sinclair
University of Birmingham
Keeron Stone
Lecturer in Cardiovascular Physiology
Cardiff University
Sveinung Berntsen
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Susan P Mollan
University Hospitals Birmingham NHS Foundation Trust
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