Sandra Minotti

McGill University

Canada

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Articles (4)

Year:

2024

Year:

2024

Year:

2022

Year:

2020

Collaborators (2)

Benoit GENTIL

Assistant Professor

McGill University

CANADA

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Laetitia Marcadet

Professionnelle de recherche

Laval University

CANADA

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Sandra Minotti

Research Interests

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Articles (4)

Reversal of cognitive deficits in FUS<sup>R521G</sup> amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat shock protein induction.

Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS.

The J Domain of Sacsin Disrupts Intermediate Filament Assembly

Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models.

Collaborators (2)

Benoit GENTIL

Laetitia Marcadet

Make your next move.

Sandra Minotti

Research Interests

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Contact this professor

Articles (4)

Reversal of cognitive deficits in FUS&lt;sup&gt;R521G&lt;/sup&gt; amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat shock protein induction.

Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS.

The J Domain of Sacsin Disrupts Intermediate Filament Assembly

Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models.

Collaborators (2)

Benoit GENTIL

Laetitia Marcadet

Make your next move.

Reversal of cognitive deficits in FUS<sup>R521G</sup> amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat shock protein induction.