Sangsu Bae

Associate Professor

Seoul National University College of Medicine

South Korea

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About

Dr. Sangsu Bae is an Associate Professor at Seoul National University College of Medicine in South Korea. His research focuses on genome editing technologies, including advancements in CRISPR-Cas9 methodologies, base editing, and their therapeutic applications for genetic diseases. Recent publications highlight his contributions to improving editing efficiency and exploring genome editing in plants and human pluripotent stem cells.

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2025

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2022

Collaborators (10)

Mi-Jeong Ahn

Gyeongsang National University

SOUTH KOREA

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Professor

Seoul National University

SOUTH KOREA

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Sangsu Bae

Research Interests

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About

Articles (20)

A rational engineering strategy for structural dynamics modulation enables target specificity enhancement of the Cas9 nuclease

AI-generated MLH1 small binder improves prime editing efficiency

Identification of optimal adenine and cytosine base editors for genome editing in Arabidopsis and soybean

Therapeutic Applications of Genome Editing Tools for Genetic Diseases

Autophagy induction enhances homologous recombination-associated CRISPR–Cas9 gene editing

Phenotypic characterization of pre-harvest sprouting resistance mutants generated by the CRISPR/Cas9-geminiviral replicon system in rice

Author Correction: Enhancing genome editing in hPSCs through dual inhibition of DNA damage response and repair pathways

Enhancing genome editing in hPSCs through dual inhibition of DNA damage response and repair pathways

Current status of genome editing technologies: special issue of BMB Reports in 2024

Genome-wide in-locus epitope tagging of Arabidopsis proteins using prime editors

Direct measurement of engineered cancer mutations and their transcriptional phenotypes in single cells

Two-Channel OTDM System for Data-Center Interconnects: A Review

Author Correction: Voyage to minimal base editors

High expression of uracil DNA glycosylase determines C to T substitution in human pluripotent stem cells

Genome Editing of Golden SNP-Carrying Lycopene Epsilon-Cyclase (LcyE) Gene Using the CRSPR-Cas9/HDR and Geminiviral Replicon System in Rice

Biochemical Characterization of Orange-Colored Rice Calli Induced by Target Mutagenesis of OsOr Gene

Transcriptome and Metabolite Profiling of Tomato SGR-Knockout Null Lines Using the CRISPR/Cas9 System

Voyage to minimal base editors

Therapeutic base editing and prime editing of COL7A1 mutations in recessive dystrophic epidermolysis bullosa

Comprehensive analysis of prime editing outcomes in human embryonic stem cells

Collaborators (10)

Mi-Jeong Ahn

Jihyeon Yu

Yong-Gu Cho

Heonseok Kim

Sunghyun Bae

Keewon Sung

Hyongbum Henry Kim

Hyuk-Jin Cha

Kyoungmi Kim

Seong Keun Kim

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