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Sarah Richardson

Associate Professor in Cellular Biomedicine

University of Exeter

United Kingdom

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Research Interests

Immunology

60%

Cell Biology

50%

Islet Biology

100%

Diabetology

80%

Inflammatory Biology

40%

Insulin Resistance

40%

T Cell Biology

30%

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Recent Grants

Grant: Close

Phenotype and specificity of the islet inflammation in Type 1 diabetes

Open Date: 2018-06-01

Close Date: 2020-06-01

Grant: Close

The JDRF nPOD-Virus Group: Towards Vaccine Development

Open Date: 2017-11-01

Close Date: 2019-11-01

Grant: Close

Type 1 diabetes genetic risk and persistent beta cell enteroviral infection - a lethal combination?

Open Date: 2017-03-31

Close Date: 2020-03-30

Grant: Close

Type 1 diabetes genetic risk and persistent beta cell enteroviral infection - a lethal combination?

Open Date: 2017-03-31

Close Date: 2020-12-31

Grant: Close

Characterisation of immune cell interactions in the insulitic infiltrate of patients with recent-onset type 1 diabetes

Open Date: 2017-01-01

Close Date: 2019-12-31

Articles22

Challenges and Opportunities for Understanding the Pathogenesis of Type 1 Diabetes: An Endocrine Society Scientific Statement

Article Link

Year:

2025

Quantitative analysis of human adult pancreatic histology reveals separate fatty and fibrotic phenotypes in type 2 diabetes

Article Link

Year:

2025

The Heterogeneity of Type 1 Diabetes: Implications for Pathogenesis, Prevention, and Treatment—2024 Diabetes, Diabetes Care, and Diabetologia Expert Forum

Article Link

Year:

2025

The Heterogeneity of Type 1 Diabetes: Implications for Pathogenesis, Prevention, and Treatment—2024 Diabetes, Diabetes Care, and Diabetologia Expert Forum

Article Link

Year:

2025

The heterogeneity of type 1 diabetes: implications for pathogenesis, prevention, and treatment—2024 Diabetes, Diabetes Care, and Diabetologia Expert Forum

Article Link

Year:

2025

Joint analysis of the nPOD-Virus Group data: the association of enterovirus with type 1 diabetes is supported by multiple markers of infection in pancreas tissue

Article Link

Year:

2025

Soluble HLA Class I Is Released From Human β-Cells Following Exposure to Interferons.

Article Link

Year:

2025

Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes.

Article Link

Year:

2025

Type 1 Diabetes Genetic Risk Contributes to Phenotypic Presentation in Monogenic Autoimmune Diabetes.

Article Link

Year:

2025

Interferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells.

Article Link

Year:

2025

Regulation of STAT1 Signaling in Human Pancreatic β-Cells by the Lysine Deacetylase HDAC6: A New Therapeutic Opportunity in Type 1 Diabetes?

Article Link

Year:

2024

Mesenchymal stromal cells and their secretory products reduce the inflammatory crosstalk between islets and endothelial cells

Article Link

Year:

2024

Differential expression of genes controlling lymphocyte differentiation and migration in two distinct endotypes of type 1 diabetes

Article Link

Year:

2023

Milder loss of insulin-containing islets in individuals with type 1 diabetes and type 2 diabetes-associated TCF7L2 genetic variants

Article Link

Year:

2023

Images From the Exeter Archival Diabetes Biobank Now Accessible via Pancreatlas

Article Link

Year:

2022

Live enteroviruses, but not other viruses, detected in human pancreas at the onset of type 1 diabetes in the DiViD study

Article Link

Year:

2022

Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage

Article Link

Year:

2022

Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration.

Article Link

Year:

2022

Temporal regulation of interferon signalling in human EndoC-βH1 cells.

Article Link

Year:

2022

Editorial: Immunopathology of Type 1 Diabetes.

Article Link

Year:

2022

Expression of CD47 in the pancreatic β-cells of people with recent-onset type 1 diabetes varies according to disease endotype.

Article Link

Year:

2021

Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection.

Article Link

Year:

2021

Collaborators21

Aaron Michels

Associate Professor

University of Colorado School of Medicine

UNITED STATES

Amir-Babak Sioofy-Khojine

University of Tampere

FINLAND

Roberto Mallone

Université Paris Cité

FRANCE

Riitta Veijola

Professor and Chief Physician in Paediatrics

Oulu University Hospital

FINLAND

DANIELA CAMPANI

Associate Professor

University of Pisa

ITALY

Todd Brusko

Professor/Scientific Director

University of Florida

UNITED STATES

Åke Lernmark

Lund University

SWEDEN

Julius O Nyalwidhe

Professor and Director, George L Wright Jr Center for Biomedical Proteomics

Eastern Virginia Medical School

UNITED STATES

Kyle Wedgwood

Associate Professor

University of Exeter

UNITED KINGDOM

Stephen Rich

Harrison Professor and Founding Director (Emeritus)

University of Virginia

UNITED STATES

Michael R. Christie

UNITED KINGDOM

Knut Dahl-Jorgensen

Senior Professor

University of Oslo

NORWAY

Dirk Homann

Icahn School of Medicine at Mount Sinai

UNITED STATES

Mark Peakman

King’s College London

UNITED KINGDOM

Noel G Morgan

University of Exeter Medical School

UNITED KINGDOM

Alberto Pugliese

Chair and Professor

Beckman Research Institute, City of Hope

UNITED STATES

sami oikarinen

University of Tampere

FINLAND

Mark Turner

Reader / Associate Professor

University of Nottingham

UNITED KINGDOM

Gareth Hawkes

Lecturer in Health Data Science

University of Exeter

UNITED KINGDOM

Maria J. Redondo

Baylor College of Medicine

UNITED STATES

James Shaw

Clinical Professor/Consultant

Newcastle University

UNITED KINGDOM

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