Todd Brusko

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Professor/Scientific Director

University of Florida

United States

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Recent Grants

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Engineered Tregs to block autoantibody development and progression of type 1 diabetes

Open Date: 2019-09-01

Close Date: 2020-09-30

Grant: Close

Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions

Open Date: 2019-08-01

Close Date: 2024-07-31

Grant: Close

Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions

Open Date: 2019-08-01

Close Date: 2024-07-31

Grant: Close

Single cell sequencing for islet-reactive T cell clonotype and transcript signatures

Open Date: 2019-06-01

Close Date: 2022-04-30

Grant: Close

A 3D Tissue Map of the Human Lymphatic System

Open Date: 2018-09-14

Close Date: 2022-06-30

Articles (11)

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2024

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2023

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2022

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2022

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2022

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2022

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2022

Collaborators (16)

Rhonda Bacher

Associate Professor

University of Florida

UNITED STATES

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Benjamin Keselowsky

UNITED STATES

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Sarah Richardson

Associate Professor in Cellular Biomedicine

University of Exeter

UNITED KINGDOM

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Allison Bayer

Associate Professor

University of Florida

UNITED STATES

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Edward Phelps

Assistant Professor

University of Florida

UNITED STATES

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Helena Elding Larsson

Lund University

SWEDEN

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Laura M. Jacobsen

University of Florida

UNITED STATES

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Megan Levings

Professor

The University of British Columbia

CANADA

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Richard McIndoe

Professor

Augusta University

UNITED STATES

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Dirk Homann

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Alberto Pugliese

Chair and Professor

Beckman Research Institute, City of Hope

UNITED STATES

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Timothy Tree

Professor in Immune Regulation and Immunotherapy

King’s College London

UNITED KINGDOM

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Gregory Marshall

Associate Professor

Brenau University

UNITED STATES

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Markus Mattila

University of Tampere

FINLAND

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Ashok Sharma

Augusta University

UNITED STATES

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Maria J. Redondo

Baylor College of Medicine

UNITED STATES

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Todd Brusko

Research Interests

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Recent Grants

Articles (11)

NADPH Oxidase 2–Derived Reactive Oxygen Species Promote CD8+ T Cell Effector Function

Milder loss of insulin-containing islets in individuals with type 1 diabetes and type 2 diabetes-associated TCF7L2 genetic variants

Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells

Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability

Immune engineered extracellular vesicles to modulate T cell activation in the context of type 1 diabetes

Biomaterials‐based nanoparticles conjugated to regulatory T cells provide a modular system for localized delivery of pharmacotherapeutic agents

Is staff consistency important to parents’ satisfaction in a longitudinal study of children at risk for type 1 diabetes: the TEDDY study

Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study

Heterogeneity of DKA Incidence and Age-Specific Clinical Characteristics in Children Diagnosed With Type 1 Diabetes in the TEDDY Study

Guidelines for standardizing T-cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes

Improving the Prediction of Type 1 Diabetes Across Ancestries.

Collaborators (16)

Rhonda Bacher

Benjamin Keselowsky

Sarah Richardson

Allison Bayer

Edward Phelps

Helena Elding Larsson

Laura M. Jacobsen

Megan Levings

Richard McIndoe

Dirk Homann

Alberto Pugliese

Timothy Tree

Gregory Marshall

Markus Mattila

Ashok Sharma

Maria J. Redondo

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