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Saskia de Wildt

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Professor of Clinical Pharmacology, pediatric intensivist

Radboud University

Netherlands

Research Interests

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Professors in Netherlands

Recent Grants

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PETIT: PEdiaTric Intestinal drug Transport, elucidating the information gap

Open Date: 2018-09-01

Close Date: 2020-08-01

Grant: Close

conect4children (COllaborative Network for European Clinical Trials For Children)

Open Date: 2018-05-01

Close Date: 2024-04-30

Grant: Close

Infradev - European Paediatric Translational Research Infrastructure

Open Date: 2018-01-01

Close Date: 2019-12-31

Grant: Close

Paediatric Clinical Research Infrastructure Network

Open Date: 2017-01-01

Close Date: 2020-12-31

Grant: Close

Labeling of Enalapril from Neonates up to Adolescents

Open Date: 2013-11-01

Close Date: 2018-10-31

Articles (23)

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Collaborators (8)

Pieter De Cock

Assistant professor

Ghent University

BELGIUM

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Stef Schouwenburg

Erasmus University Medical Center

NETHERLANDS

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karel allegaert

Researcher

Erasmus University Rotterdam

NETHERLANDS

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Tim Preijers

Hospital Pharmacist drug development & innovation and Assistant Professor Clinical Pharmacometrics

Erasmus MC

NETHERLANDS

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Anne-Sylvie Ramelet

Professor of Nursing

University of Lausanne

SWITZERLAND

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Rick Greupink

Radboud University Medical Center

NETHERLANDS

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Gwenaelle De Clifford-Faugère

University Hospital of Geneva

SWITZERLAND

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Bryony Franklin

University College London

UNITED KINGDOM

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Saskia de Wildt

Research Interests

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Recent Grants

Articles (23)

Neonatal PBPK model of midazolam and its metabolites for perinatal asphyxia and therapeutic hypothermia

Corrigenda: Pain, Agitation, Delirium, and Iatrogenic Withdrawal Syndrome Management in Children Who Are Critically Ill: Protocol for a European Clinical Practice Guideline Using the Grading of Recommendations Assessment, Development, and Evaluation Approach

Development, Early Verification and Application of a North American Pediatric PBPK Model, Comparison With the North European Pediatric Population

Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

Children with suspected anterior cutaneous nerve entrapment syndrome (ACNES), it’s not all the abdominal wall

Low Target Attainment of Intravenous Cefuroxime in Critically Ill Term Neonates and Children: A Pooled Population Pharmacokinetics Study

Pain, Agitation, Delirium, and Iatrogenic Withdrawal Syndrome Management in Children Who Are Critically Ill: Protocol for a European Clinical Practice Guideline Using the Grading of Recommendations Assessment, Development, and Evaluation Approach

A User‐Driven Framework for Dose Selection in Pregnancy: Proof of Concept for Sertraline

Physiologically Based Pharmacokinetic Modeling-Based Evaluation of Current Carbamazepine and Valproic Acid Dosing Guidelines for Pediatric Epilepsy Treatment

Optimization of the betamethasone and dexamethasone dosing regimen during pregnancy: a combined placenta perfusion and pregnancy physiologically based pharmacokinetic modeling approach

Targeted Therapy for Complex Lymphatic Anomalies in Patients with Noonan Syndrome and Related Disorders

Barriers and Facilitators for Bringing Model‐Informed Precision Dosing to the Patient's Bedside: A Systematic Review

Physiologically‐Based Pharmacokinetic Modeling for Drug Dosing in Pediatric Patients: A Tutorial for a Pragmatic Approach in Clinical Care

Guiding future paediatric drug studies based on existing pharmacokinetic and efficacy data: Cardiovascular drugs as a proof of concept

Guiding future paediatric drug studies based on existing pharmacokinetic and efficacy data: Cardiovascular drugs as a proof of concept

Use of Developmental Midazolam and 1-Hydroxymidazolam Data with Pediatric Physiologically Based Modeling to Assess Cytochrome P450 3A4 and Uridine Diphosphate Glucuronosyl Transferase 2B4 Ontogeny In Vivo

Proenkephalin A as a marker for glomerular filtration rate in critically ill children: validation against gold standard iohexol GFR measurements

Proenkephalin A as a marker for glomerular filtration rate in critically ill children: validation against gold standard iohexol GFR measurements

Physiologically Based Pharmacokinetic (PBPK) Model-Informed Dosing Guidelines for Pediatric Clinical Care: A Pragmatic Approach for a Special Population

Physiologically Based Pharmacokinetic (PBPK) Model-Informed Dosing Guidelines for Pediatric Clinical Care: A Pragmatic Approach for a Special Population

Use of xylometazoline in hospitalised infants: is it safe? A retrospective cohort study

Use of xylometazoline in hospitalised infants: is it safe? A retrospective cohort study

Collaborators (8)

Pieter De Cock

Stef Schouwenburg

karel allegaert

Tim Preijers

Anne-Sylvie Ramelet

Rick Greupink

Gwenaelle De Clifford-Faugère

Bryony Franklin

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